Seminars list
On the multiple roads to cell fate decisions: Integrating transcription factors into RNA-regulatory networksWhile the current view states that Transcription Factors (TFs) act on DNA regulatory elements to deploy precise gene programs, an emerging concept proposes that TFs also bind RNA and regulate splicing to promote molecular and cellular diversity. Yet, how the RNA regulatory functions of TFs contri... |
Scientific Publishing: Behind the Scenes at NatureA fundamental part of scientific research is publishing your research findings. But once you have submitted your paper to a journal, it can seem like a daunting black box regarding what actually happens to your paper and how authors can successfully navigate the various steps of the publication p... |
Demystifying Machine and Deep Learning and overview of their applications in biologyArtificial Intelligence is a broad term that is often misunderstood. Its subfields, such as machine and deep learning have achieved astonishing performances, such as some Large Language Models passing the Turing Test or AlphaFold offering a solution to a 50 years old problem. Because new technolo... |
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTIONClaude Desplan1,2, Nikos Konstantinides1, Felix Simon1, Neset Ozel1, Isabel Holguera1, Jennifer Malin1, Yen Chen1, and Bogdan Sieriebriennikov1 1 Center for Developmental Genetics, Department of Biology, New York University, New York, USA; 2 Center for Genomics and System Biology, NYU Abu... |
Common threads in regeneration: mechano-chemical insights from a jellyfish modelHow randomly injured animals can appropriately re-establish positional information and control the deployment of repair programs are key questions of regenerative biology. The hydrozoan jellyfish Clytia hemisphaerica has recently emerged as an original model organism for probing repair phenomena,... |
 Friday, May 3rd, 2024 - Seminar Speaker(s) : Anne Brunet (Stanford University School of Medicine) Understanding and modeling agingAging is associated with a decline in tissue function and the onset of a constellation of diseases. We are interested in understanding aging, with a particular focus on brain aging. Because aging is complex, we use organisms with diverse lifespans – the worm C. elegans, the African killifis... |
Protect and recycle: how cells regulate dormancyOur research is focused on elucidating how cell growth and division are regulated in space and time, in particular by selective degradation of cellular components. Eukaryotic cells use autophagy and the ubiquitin-​proteasome system (UPS) to ensure cellular homeostasis, and recycle excess an... |
 Monday, May 13th, 2024 - Seminar Speaker(s) : Jeroen Roose (University of California, San Francisco) Deconstruct-Reconstruct Decode cancer-immune crosstalk & probe with organoids.The Roose team at UCSF studies mechanisms of cell-cell interactions in immunology and cancer1-7, with emphasis on personalized medicine4,8 and single cell approaches9-11. Over the past 7 years, we shifted a large portion of our research efforts to understanding human biology and disease. We are d... |
How do single bacterial cells think?The functioning of genome-wide gene regulatory networks in bacteria presents us with an apparent paradox. On the one hand, bacterial populations successfully coordinate their gene expression patterns and phenotypes to allow them to grow in a huge variety of environments, including complex combina... |
Cell Size ControlCell size plays a crucial role in the function of various cell types throughout the human body, influencing organelle structure, biosynthesis, and surface transport processes. Although certain genes influencing cell size have been identified, the molecular mechanisms by which cell growth initiate... |