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  • Tuesday, 27th, February 2024 - Séminaire Speaker(s) : Samuel Safran

    Liquid-liquid phase separation (LLPS): Non-equilibrium effects at the mesoscale

    Phase separation is generally a thermodynamic process in which a mixture reaches its lowest free energy state by self-assembling into meso- (or macro-) scale regions that are concentrated or dilute in a given molecular component.  A rapidly growing body of experiments suggests that phase separati...

  • Wednesday, 28th, February 2024 - Séminaire Speaker(s) : Rosalia Moreddu

    Recording bioelectric signaling in human breast cancer cells and cell networks

    Cancer cells are known to exhibit abnormal electrical properties compared to their healthy counterparts, and this has driven researchers to investigate the potential of harnessing bioelectricity as a tool in cancer diagnosis, prognosis, and treatment. In parallel, cancer bioelectricity represents...

  • Wednesday, 28th, February 2024 - Séminaire institutionnel "Mayent - Rothschild" Speaker(s) : Dan Larson

    Spliceosome Mutations in Myeloid Malignancy

    The primary goal of Dan Larson's laboratory is to understand gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue. The laboratory utilizes a battery of biophysical, molecular and genomic ap...

  • Thursday, 29th, February 2024 - Séminaire Speaker(s) : Jelle van den Ameele (MRC Mitochondrial Biology Unit and Department of Clinical Neurosciences, University of Cambridge, UK)

    Metabolism of neural stem cell-niche interactions

    Metabolism of neural stem cell – niche interactions While almost all eukaryotic cells require mitochondrial energy production, not all cells and tissues are equally susceptible to mitochondrial disease. In our lab, we mainly study how mitochondrial dysfunction and mutations in the mitoch...

  • Friday, 8th, March 2024 - Séminaire Speaker(s) : Patrick Rochette (Centre de recherche du CHU de Québec – Université Laval)

    Solar radiation and pollution: a mitochondrial perspective.

    Although the mitochondrion is central to the genotoxic stress response, it has not received the attention commensurate with its importance. Thanks to the development of novel methods for isolating and internalizing functional mitochondria as well as techniques to analyze their condition, we can n...

  • Monday, 11th, March 2024 - Symposium Speaker(s) : Vincent Colot, Wolf-Dietrich Heyer, Franz Klein, Steve Kowalczykowski, Michael Lichten, Sophie Loeillet, Bernard de Massy, Christine Mézard, Rodney Rothstein, Xavier Sastre-Gareau, Jack Szostak, Marie-Paule Teulade-Fichou, Steve West, Denise Zickler

    "Genetics together with the next-generation" - Un symposium pour célébrer la carrière d'Alain Nicolas

    Le symposium "Genetics together with the next-generation" honorera la carrière d'Alain Nicolas, qui s'est consacré à l'étude des mécanismes de maintenance des génomes et de transmission intergénérationnelle. Au-delà de ses nombreuses contributions scientifiques, Alain a également contribué à form...

  • Monday, 11th, March 2024 - Séminaire Immunology series Speaker(s) : Wolfgang Kastenmüller (University of Würzburg, Institute of Systems Immunology)

    T cell dynamics in lymph node microdomains scaling CD8 Teff formation

    In my seminar I will give an overview of our current knowledge about spatio-temporal events during CD8 T cell priming after viral infections. I will show data how the communication between CD4+, CD8+ T cells and Treg cells is orchestrated in the LN, thereby revealing a new dynamic phase of T cell...

  • Wednesday, 13th, March 2024 - Séminaire Speaker(s) : Weria Pezeshkian

    Computational Microscopy of Biomembranes: bridging the gap between simple models and complex reality

    Biomembranes are fundamental to cell biology. They are a complex two-dimensional fluid, composed of myriad proteins and lipid species, which provide identity to the cell and to many internal organelles. Membrane spatial (shape) and lateral organization are two intriguing aspects of biomembranes, ...

  • Tuesday, 19th, March 2024 - Séminaire Speaker(s) : Ivaylo Ivanov (University of Alabama at Birmingham)

    Microbiota-immune interactions in health and disease

    Commensal microbes induce tissue-resident T cells, but the function of these T cells is not well understood. In this lecture I will present our latest data on the role of commensal Th17 cells in mucosal homeostasis and host physiology. I will explore how commensal Th17 cells in the small intestin...

  • Wednesday, 20th, March 2024 - Séminaire Speaker(s) : Anne Marie Wehenkel

    Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation

    The order Corynebacteriales includes major industrial and pathogenic actinobacteria such as Corynebacterium glutamicum or Mycobacterium tuberculosis. Their elaborate multi-layered cell wall and their polar growth mode impose a stringent coordination between the septal divisome, organized around t...

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