Liste des séminaires
Microbiota-immune interactions in health and diseaseCommensal microbes induce tissue-resident T cells, but the function of these T cells is not well understood. In this lecture I will present our latest data on the role of commensal Th17 cells in mucosal homeostasis and host physiology. I will explore how commensal Th17 cells in the small intestin... |
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongationThe order Corynebacteriales includes major industrial and pathogenic actinobacteria such as Corynebacterium glutamicum or Mycobacterium tuberculosis. Their elaborate multi-layered cell wall and their polar growth mode impose a stringent coordination between the septal divisome, organized around t... |
A garden of forking paths: branching, switching and reversal in meiotic recombinationMeiotic recombination involves repair of double strand DNA breaks by homologous recombination to form crossovers and noncrossovers. Current models suggest that different mechanisms form these two products: noncrossovers by synthesis dependent strand annealing; COs by double Holliday junction form... |
Structural neutrophilsTissues are composed of cells from different lineages that fulfil different roles needed for organ function. As technologies develop and we expand the palette of immune functions, however, the functional divide between lineages disappear. In this talk I will provide an example that illustrates th... |
Dynamic chromosome conformation signatures as prognostic and diagnostic disease biomarkers and their relationship to the non-coding nascent transcriptomeWe are interested in the stable fractal-like folded network adopted by eukaryotic genomes. We use two approaches to uncover these folded states. First is a proprietary machine learning algorithm that assigns potential contact points in the genome, which are regions with a high propensity to fold... |
Regulation and immunotherapy responses of NK cells (and T cells) against tumorsMost immunotherapy efforts aim to mobilize CD8+ T cells against cancer cells. Many tumors lack many neoantigens, and others are selected for partial or complete loss of MHC I, even before immunotherapy intervention. Checkpoint immunotherapy further exacerbates this problem as it preferentially a... |
Biophotonics, Robots, GhostsIn this talk, I will discuss two qualitatively new directions in biophotonics: i) FLUCS & interactive microscopy: We have made efforts to understand and control cellular organization through the induction of thermoviscous flows. This includes the non-invasive interference and guidance of PAR p... |
Spatiotemporal models of mammalian development: An epigeneticists dream or nightmare?My research group aims to address the fundamental challenge of understanding how multicellular organisms achieve variation despite cells having identical genetic information. The development of a single fertilized egg into a complete mammalian embryo is an especially beautiful embodiment of this ... |
Together for inclusion at the Institut Curie: Autism at workWithin the context of World Autism Awareness Day Do you know how the unique talents of people with autism can transform the professional world? Discover the answers at our Autism Awareness Conference! Explore the diversity and unique talents present in the autism spectrum. What you'll l... |
Ensemble pour l'Inclusion à l'Institut Curie : LAutisme au travailWebinaire proposé dans le cadre de la Journée mondiale de sensibilisation à l'autisme Savez-vous comment les talents uniques des personnes autistes peuvent transformer le monde professionnel ? Découvrez les réponses lors de notre conférence de sensibilisation sur l'autisme ! Explorez la di... |