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  • Mardi 3 Septembre 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem)

    Pluripotent stem cell models reveal altered genetic and epigenetic pathways in Huntington’s disease

    I will discuss juvenile and infantile forms of human pluripotent stem cell (hPSC) isogenic models for Huntington's disease (HD), the most common poly-glutamine (polyQ) related disorder. HD is caused by CAG (encoding glutamine, Q) expansions within the Huntingtin (HTT) gene. The aberrant polyQ-con...

  • Mardi 10 Septembre 2024 - Séminaire Orateur(s) : Mauro Gaya (Centre d'Immunologie de Marseille Luminy ), Mariolina Salio (Immunocore LTD, Abingdon UK)

    “B cell memory in barrier tissues” - " From the bench to the bedside: cancer immunotherapy with soluble T cell receptors"

    B cell memory in barrier tissues During infection, the immune system unleashes protective responses to fight against the pathogen while also establishes a memory compartment that will provide protection in case of a subsequent pathogen encounters. The B cell memory compartment is composed of t...

  • Mercredi 11 Septembre 2024 - Séminaire Orateur(s) : Yoël Forterre

    From perception to action without nerves and muscles: lessons from plants

    As sessile organisms, plants face a constantly changing environment with no means of escape. Thus, despite their lack of nerves and muscles, they have evolved unique mechanisms to perceive and respond to external physical signals. In this seminar, I will illustrate this ability through two emblem...

  • Lundi 16 Septembre 2024 - Séminaire Immunology series Orateur(s) : Enfu Hui (Department of Cell and Developmental Biology, UCSD, San Diego)

    When Nuance Matters: The lesser known side of PD1 signaling

    The inhibitory immunoreceptor PD1 is a major cancer immunotherapy target. Anti-PD1 blockade antibodies have become the standard of care for cancer patients, but the low response rate and associated immune related side effects necessitate a better understanding of PD1 mechanism. Best known to be e...

  • Lundi 16 Septembre 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem)

    Epigenetics: from human pluripotent stem cell models of neurodegenerative diseases to recent human evolution

    In the first part, I will discuss juvenile and infantile forms of human pluripotent stem cell (hPSC) isogenic models for Huntington's disease (HD), the most common poly-glutamine (polyQ) related disorder. HD is caused by CAG (encoding glutamine, Q) expansions within the Huntingtin (HTT) gene. The...

  • Du Lundi 30 Septembre 2024 Au Vendredi 4 Octobre 2024 - Cours international - séminaire

    Analyse spatiale de données multimodales : quand les omiques rencontrent les images (Biologie des Systèmes du Cancer)

    Le cours réunira des intervenants de premier plan issus de différents domaines de la biologie des systèmes cancéreux, de la recherche sur le cancer et de la clinique. Les orateurs invités exposeront diverses approches pour l'analyse et l'interprétation des données omiques, d'imagerie et cliniques...

  • Lundi 7 Octobre 2024 - Séminaire Orateur(s) : Luca Magnani (Institute of Cancer Research)

    Breast Cancer Dormancy: A Link to the Past

    Luca Magnani graduated from his bachelor's and master's degree at the University of Bologna. During an exchange visit to Purdue University, he discovered his interest in early embryogenesis. Dr. Magnani's work took him to Michigan State University, where he continued his research on mouse embryog...

  • Mardi 8 Octobre 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem)

    Epigenetics: from pluripotent stem cells to ancient DNA

    Pluripotent embryonic stem cells (ESCs) are characterized by a unique, globally decondensed, chromatin structure. In the first and main part will describe our endogenously-tagged fluorescent-fusion protein libraries in mouse ESCs, which we used to screen for potential regulators of pluripotency a...

  • Mardi 15 Octobre 2024 - Séminaire Orateur(s) : Sara Lucia Giustina Sigismund

    Endocytic control of cell plasticity in cancer

    Over the past two decades, there has been a significant shift in our understanding of the role of endocytosis and trafficking of signaling receptors. It has evolved from being viewed simply as a signal extinguisher (resulting in long-term attenuation) to being recognized as a sophisticated mechan...

  • Du Lundi 14 Octobre 2024 Au Vendredi 18 Octobre 2024 - Cours international - séminaire

    6th International Breast Cancer Course - From Clinics to Biology

    This 6th edition of the international breast cancer course organized by the Institut Curie offers a comprehensive overview of current topics on clinical and biological aspects of breast cancer. This course brings together internationally renowned experts who will present the latest innovations in...

  • Du Lundi 21 Octobre 2024 Au Mercredi 30 Octobre 2024 - Cours international - séminaire

    Developmental Biology: from stem cells to morphogenesis - 15th edition

    Institut Curie and Sorbonne Université organize their 15th International Developmental Biology course. The aim of the program is to provide the participants a comprehensive coverage of the paradigms, problems and technologies of modern Developmental Biology paying particular attention to stem ...

  • Du Mardi 12 Novembre 2024 Au Vendredi 15 Novembre 2024 - Cours international - séminaire

    Advanced Course on Immunity and Cancer Immunotherapy 2024

    The Immunity and Cancer Unit of Institut Curie (INSERM U932) is organizing the 7th edition of the Advanced Course on Immunity and Cancer Immunotherapy. In the context of ongoing cooperation projects with research teams in Chile and Argentina that have resulted in the prior organization of work...

  • Du Mardi 12 Novembre 2024 Au Vendredi 15 Novembre 2024 - Cours international - séminaire

    Advanced Course on Immunity and Cancer Immunotherapy 2024

    The Immunity and Cancer Unit of Institut Curie (INSERM U932) is organizing the 7th edition of the Advanced Course on Immunity and Cancer Immunotherapy. In the context of ongoing cooperation projects with research teams in Chile and Argentina that have resulted in the prior organization of work...

  • Mercredi 12 Mars 2025 - Séminaire Orateur(s) : Thorsten Hugel

    Compartment-specific protein dynamics and signalling in living cells revealed by smFRET

    Proteins in cells are not homogeneously distributed, but often localized to specific compartments, which may or may not be enclosed by membranes.   Here I will first discuss the dynamic formation of membraneless compartments in the non-equilibrium environment of living cells and how this formati...

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