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  • Mardi 26 Mars 2019 - Séminaire Cell Biology Series Orateur(s) : Jérôme DEJARDIN (Institute of Human Genetics - Team "Biology of Repetitive Sequences" - Montpellier)

    Chromatin based regulation of telomere maintenance

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  • Mardi 26 Mars 2019 - Séminaire

    4e journée annuelle cancer du sein - inscrivez-vous!

    Actualités de la recherche cancer du sein à Curie et nouvelles perspectives. Si vous souhaitez participer au déjeuner merci de bien vouloir vous inscrire en cliquant ici (avant le 20 mars 2019) 8h30 – 8h45 Introduction Le cancer du sein à Curie : PMS et SIRIC, état des lieux - M...

  • Mercredi 27 Mars 2019 - Séminaire Orateur(s) : Allen Liu (Mechanical Engineering, University of Michigan)

    Mechanobiology of Biological Membranes: from Mechanotransduc​tion to Artificial Cells

     Biological membranes are involved in a large number of cellular processes including cell migration, membrane trafficking, and cell signaling. Significant amount of work have elucidated the molecular machineries that regulate dynamic membrane-based processes. In parallel, there are growing intere...

  • Vendredi 29 Mars 2019 - Séminaire Orateur(s) : Eric Chevet (NSERM U1242, “Chemistry, Oncogenesis, Stress, Signaling”, Université de Rennes, Rennes, France. Centre de Lutte Contre le Cancer Eugène Marquis, Rennes, France.)

    Endoplasmic Reticulum proteostasis in cancer development

    Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Genetic and pharmacological evidence suggest that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer development. This concept is vali...

  • Lundi 1 Avril 2019 - Séminaire Orateur(s) : Linda Partridge

    Drugging Ageing

    Ageing is malleable to genetic, dietary and pharmacological interventions. Furthermore, its underlying mechanisms have proved to be conserved over long evolutionary distances. Ageing is the main risk factor for chronic and killer diseases, and in animal models interventions that ameliorate ageing...

  • Vendredi 5 Avril 2019 - Symposium

    10e Journée ROGER MONIER - Imaging : a revolution

    Meeting co-sponsored by Gustave Roussy and Institut Curie that honors the memory of Professor Roger Monier, a prominent figure in French modern biology. This year, we celebrate the 10th edition, a scientific day meeting focuses on a forefront issues in cancer biology: « Imaging: a revolution »...

  • Mercredi 10 Avril 2019 - Séminaire Orateur(s) : Liliya A. Yatsunyk (Chemistry and Biochemistry, Swarthmore College)

    Structural and Biophysical Studies of non-canonical DNA

      This talk will cover two representative stories on our attempts to elucidate the structure of non-canonical DNA implicated in important biological processes. To accomplish this goal we used a variety of biophysical methods coupled with X-ray crystallography. The first project concerns (CAGAG...

  • Jeudi 11 Avril 2019 - Séminaire Orateur(s) : Rudy Van Eijsden (Sr. Product Application Scientist (EMEA) )

    NanoString nCouner direct digital counting - Flexible High Plex biomarker research without RT and amplification bias

         

  • Vendredi 12 Avril 2019 - Séminaire Orateur(s) : Olivier Pertz (Institute of Cell Biology, University of Bern)

    Decoding and re-encoding MAPK fate decision signaling

    Cells dynamically sense and respond to ever changing external stimuli through sophisticated signaling networks. Accordingly, signaling dynamics rather than steady states have been recently shown to control cell fate decisions. For multiple signaling systems, heterogeneous dynamic signaling states...

  • Mercredi 17 Avril 2019 - Séminaire Orsay series Orateur(s) : Kara L. Davis (Faculty Scholar in Pediatric Cancer and Blood Diseases Stanford Child Health Research Institute)

    Understanding Leukemia through the Lens of Normal Development: Single-cell studies for Clinical Translation

    Acute leukemia is the most common cancer of childhood and one of the most deadly due to relapsed disease. Predicting patients at high risk of relapse is an imperfect science and currently combines clinical features, somatic alterations and early response to therapy. Yet, despite this, for the 20%...

  • Jeudi 18 Avril 2019 - Séminaire Orateur(s) : Molly Przeworski

    An evolutionary perspective on meiotic recombination in vertebrates

    Meiotic recombination is a fundamental genetic process that generates new combinations of alleles on which natural selection can act and ensures the proper alignment and segregation of chromosomes. Recombination events are initiated by double strand breaks deliberately inflicted on the genome dur...

  • Vendredi 19 Avril 2019 - Séminaire Orateur(s) : Arthur ALLIGNOL (Epidemiology department of Merck KGaA, Germany)

    How to analyses long-term treatment effects using Real Word Data?

    Read world data (RWD) are "Data relating to patient health status and/or delivery of health care routinely collected from a variety of sources", such as electronic health records or claims and billing activities. Such data can be used to perform cohort studies that compare the effectiveness of me...

  • Mercredi 24 Avril 2019 - Séminaire Orateur(s) : Marie-Anne Rameix-Welti (INSERM U1173 Infection - Inflammation, Université Versailles Saint-Quentin en Yvelines)

    Organization of viral RNA synthesis in Respiratory Syncytial Virus infected cells: Viral RNA granules?

    Cells infected by respiratory syncytial virus (RVS) exhibit cytoplasmic inclusion (IBs) which concentrate the components of the viral polymerase (L, P, N and M2-1) and the viral genomic RNA. Using metabolic labelling we established that viral RNA synthesis occur in IBs. We identified and characte...

  • Lundi 29 Avril 2019 - Séminaire Orateur(s) : Dr. Wulf Fischer-Knuppertz

    Unraveling Cancer Metabolism by Next-Generation Metabolomics

    Dr. Fischer-Knuppertz holds a PhD in veterinary medicine from LMU Munich, Germany, and an Executive MBA from St. Gallen Business School, Switzerland. He took over as CEO & Chairman of the Board of Biocrates Life Sciences AG on 1 June 2013. For the past 25 years, Dr Fischer-Knuppertz has filled v...

  • Jeudi 9 Mai 2019 - Séminaire

    Domain 2 Meeting

    Agenda to come.

  • Jeudi 9 Mai 2019 - Séminaire Orateur(s) : Oliver Rando (University of Massachusetts Medical School)

    TBD

    TBD

  • Vendredi 10 Mai 2019 - Séminaire Orateur(s) : Marisa Bartolomei (Perelman School of Medicine University of Pennsylvania)

    Regulation of genomic imprinting in development and disease

    Regulation of genomic imprinting in development and disease   

  • Mercredi 15 Mai 2019 - Séminaire Orsay series Orateur(s) : Núria de la Iglesia, PhD (Glioma and Neural Stem Cell Group August Pi i Sunyer Biomedical Research Institute (IDIBAPS))

    The Quest to Unravel the Complex Biology of Glioblastoma: from Genomics and Beyond

    Glioblastomas (GBMs) are the most frequent and aggressive primary tumors in the central nervous system owing to their fast clinical course and uniform lethality In the past decade, there has been a big step forward in the identification of the genomic and epigenomic alterations found in GBM pa...

  • Vendredi 17 Mai 2019 - Symposium

    A day to celebrate the career of Michel Bornens and his outstanding contribution to cell biology.

    more information to come 

  • Jeudi 20 Juin 2019 - Séminaire Orateur(s) : Trey IDEKER (UC San Diego School of Medicine)

    Decoding tumor genomes through the hierarchical pathway architecture of the cancer cell

    Although cancer is governed by complex molecular systems, the composition and modular organization of these systems remains poorly understood. I will describe efforts by the Cancer Cell Map Initiative (CCMI) to generate large protein interaction maps of tumor cells, which we are integrating with ...

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