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  • Mardi 4 Septembre 2018 - Séminaire Nuclear dynamic series Orateur(s) : Emmanuelle MARTINI (CEA)

    Homologous recombination during meiosis: the role of the ssDNA

    Abstract to come

  • Mercredi 12 Septembre 2018 - Séminaire Orateur(s) : Jakub Sedzinski (Danstem (Center for Stem Cell and Developmental Biology), Copenhague, Danemark)

    How to fit in? Emergence of an apical epithelial cell surface in vivo.

    Epithelial sheets are crucial components of all metazoan animals, enclosing organs and protecting the animal from its environment.  Epithelial homeostasis poses unique challenges, as addition of new cells and loss of old cells must be achieved without disrupting the fluid-tight barrier and apicob...

  • Mardi 18 Septembre 2018 - Séminaire Orateur(s) : Julien Dumortier (Institut Curie), Judith Mine Hattab (Institut Curie), Michael Schertzer (Institut Curie), Annabelle Gérard

    Domain 2 Meeting "Nuclear activity and cellular physics at the single cell level"

    10-10h30: Julien Dumortier (Jean-Léon Maître's team, UMR3215) Title TBD; 10:30-11h: Judith Mine Hattab (Angela Taddei's team, UMR3664) "Gimme a break: Imaging Rad52 dynamics at the single molecule level" 11h-11h30: Michael Schertzer (Arturo Londono's team, UMR3244) Title TBD; 11h30-12h: ...

  • Mardi 18 Septembre 2018 - Séminaire institutionnel "Marie Curie Seminar" Orateur(s) : Stephen J. Simpson (Charles Perkins Centre, The University of Sydney)

    Models and model systems: the nutritional geometry of health and ageing

    The question of what represents a balanced diet and how this maintains health and longevity remains unanswered. The talk will set out an integrative framework, Nutritional Geometry, for describing the multidimensional nature of nutritional requirements, the relative values of foods in relation to...

  • Mercredi 19 Septembre 2018 - Séminaire Orateur(s) : Mohamed-Ali HAKIMI

    Host-parasite coevolutionary arms: Toxoplasma effectors co-opt the host cell (epi)genetic program

    The obligate intracellular parasite Toxoplasma gondii strikes a subtle balance with the host immune system that not only prevents host death but also promotes parasite persistence. Although being enclosed within a parasitophorous vacuole (PV), the parasite actively interfaces with host cell signa...

  • Jeudi 20 Septembre 2018 - Séminaire Orateur(s) : Stephen West (Francis Crick Institute)

    A Life on Holliday

    Our genetic material (DNA) is continually subjected to damage, either from endogenous sources such as reactive oxygen species that arise as by-products of oxidative metabolism, from the breakdown of replication forks during cell growth, or by agents in the environment such as ionizing radiation o...

  • Mardi 25 Septembre 2018 - Séminaire Orateur(s) : Stefan Pfister

    Hereditary predisposition to childhood brain tumors – an underappreciated challenge?

    It has been well established that pathogenic germline mutations in genes like TP53, PTCH1, SUFU, APC, NF1, SMARCB1, SMARCA4, BRCA2 and the MMR genes are associated with an increased incidence of brain tumors. Most of them are associated with a specific type of brain tumor. It has been estimated t...

  • Vendredi 12 Octobre 2018 - Congrès

    International Marie Sklodowska-Curie Meeting: From Radiation to Innovation in Medicine

    Nous sommes heureux de vous convier au meeting, organisé par le RADIATE-ITN qui se tiendra à l'Institut Curie, le 12 octobre 2018. RADIATE est un réseau du programme de recherche et d'innovation Horizon 2020 de l'Union européenne conduit grâce au financement Marie Skłodowska-Curie*. Le...

  • Mardi 16 Octobre 2018 - Séminaire Orateur(s) : Tiago Faial

    Publishing in Nature Genetics

    Tiago Faial obtained his Ph.D. from the Stem Cell and Developmental Biology program at the University of Cambridge under the supervision of Jim Smith and Roger Pedersen, where he studied gene regulatory networks and signaling cascades that underpin mesoderm differentiation. For his postdoctoral w...

  • Mardi 30 Octobre 2018 - Séminaire Orateur(s) : Isabelle Mus-Veteau (Institut de Pharmacologie Moléculaire et Cellulaire, UMR-CNRS 7275 660, route des Lucioles, Sophia Antipolis, Valbonne, France)

    Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy Efficiency

    One of the crucial challenges in the clinical management of cancer is resistance to chemotherapeutics. Multidrug resistance (MDR) has been intensively studied, and one of the most prominent mechanisms underlying MDR is overexpression of ATP-binding cassette (ABC) transporters. Despite research ef...

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