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  • Jeudi 24 Octobre 2024 - Séminaire Keynote BDD Orateur(s) : Matthias Lütolf (EPFL, Lausanne)

    Engineering Epithelial Organoids

    Organoids form through poorly understood morphogenetic processes in which initially homogeneous ensembles of stem cells spontaneously self-organize in suspension or within permissive three-dimensional extracellular matrices. Yet, the absence of virtually any predefined patterning influences such ...

  • Mercredi 6 Novembre 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Leon Peshkin (Harvard Medical School)

    Xenopus Protein Atlas: missing proteins turn up in frogs !

    Understanding protein expression across tissues and organisms is crucial for elucidating functional similarities and differences in physiological processes, which is essential for selecting the appropriate model organism in biomedical studies. We present a comprehensive analysis of protein repert...

  • Mercredi 13 Novembre 2024 - Séminaire Orateur(s) : Gabriel Fernández Calvo

    Mathematical Perspectives on Clinical Oncology: Modelling Cancer Dynamics

    The integration of mathematical models into clinical oncology has emerged as a powerful tool for understanding and predicting cancer dynamics, with applications ranging from forecasting tumor growth and identifying prognostic biomarkers to optimizing therapeutic response. This talk will provide a...

  • Lundi 18 Novembre 2024 - Séminaire Orateur(s) : Carole Parent (Raymond and Lynne Ruddon Collegiate, Life Sciences Institute, University of Michigan)

    THE NEUTROPHIL NUCLEUS AS A SIGNALING HUB DURING CHEMOTAXIS AND DNA RELEASE

    Research in the Parent lab aims at understanding the mechanisms by which cells reach sites of infection and injury. In particular, our work focuses on neutrophils, the most abundant leukocyte in human blood and first line of defense against insult. We found that, in response to primary chemoattra...

  • Mercredi 20 Novembre 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Leon Peshkin (Harvard Medical School)

    Systems Biology with AI co-pilots: the hype, the craft and the roadmap.

    The widely anticipated revolution in biology, driven by the superpowers of GAI, has been slow to materialize. In this talk, we will discuss the concept, the obstacles, and examine two specific projects involving language and image analysis. The first case study involves extracting information fro...

  • Mardi 3 Décembre 2024 - Séminaire Orateur(s) : Anna Vähärautio (University of Helsinki)

    Tracing back primed resistance in cancer

    Treatment resistance is a major challenge in cancer care. Beyond genetic changes, non-genetic changes affecting gene expression can drive intrinsic resistance, which are harder to study due to the responsive nature of the transcriptome. To tackle this, we developed ReSisTrace, a methodology that ...

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