Seminars list
Protect and recycle: how cells regulate dormancyOur research is focused on elucidating how cell growth and division are regulated in space and time, in particular by selective degradation of cellular components. Eukaryotic cells use autophagy and the ubiquitin-​proteasome system (UPS) to ensure cellular homeostasis, and recycle excess an... |
 Monday, May 13th, 2024 - Seminar Speaker(s) : Jeroen Roose (University of California, San Francisco) Deconstruct-Reconstruct Decode cancer-immune crosstalk & probe with organoids.The Roose team at UCSF studies mechanisms of cell-cell interactions in immunology and cancer1-7, with emphasis on personalized medicine4,8 and single cell approaches9-11. Over the past 7 years, we shifted a large portion of our research efforts to understanding human biology and disease. We are d... |
How do single bacterial cells think?The functioning of genome-wide gene regulatory networks in bacteria presents us with an apparent paradox. On the one hand, bacterial populations successfully coordinate their gene expression patterns and phenotypes to allow them to grow in a huge variety of environments, including complex combina... |
Cell Size ControlCell size plays a crucial role in the function of various cell types throughout the human body, influencing organelle structure, biosynthesis, and surface transport processes. Although certain genes influencing cell size have been identified, the molecular mechanisms by which cell growth initiate... |
 Tuesday, May 21st, 2024 - Seminar Speaker(s) : Hironori Funabiki (The Rockefeller University, New York) Nucleosomes and DNA methylation implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancersDNA methylation is a broadly observed epigenetic modification. As genomic DNA methylation profiles dynamically change during development and aging, alterations in DNA methylation patterns are linked to diseases such as cancers and immunodeficiency. ICF syndrome is characterized by hypomethylation... |
 Wednesday, May 29th, 2024 - Seminar Speaker(s) : Pierre Ronceray Learning dynamical models from stochastic trajectoriesThe dynamics of biological systems, from proteins to cells to organisms, is complex and stochastic. To decipher their physical laws, we need to bridge between experimental observations and theoretical modeling. Thanks to progress in microscopy and tracking, there is today an abundance of experime... |
 From Wednesday, May 22nd, 2024 To Wednesday, May 29th, 2024 - International Course Seminar Non-Coding GenomeThe NON-CODING GENOME course will explore the versatility of non-genic DNA elements and non-coding RNAs across a spectrum of cellular processes, in humans and model organisms, and their implication in physiology and disease. Internationally recognized experts will present their latest findings re... |
 Friday, May 31st, 2024 - Seminar Speaker(s) : Wei Yang (National Institute of Health - NIH) Cutting and Pasting DNA to Create our Adaptive Immune SystemV(D)J recombination is essential for generating the adaptive immune response and unlimited number of different antibodies and antigen receptors. Encoded by multiple V, D and J gene segments, antigen receptors are assembled by programmed double-stranded DNA cleavage and imprecise re-joining. RAG1/... |
In situ structures of muscle sarcomere and sarcomeric proteinsSarcomeres are force-generating and load-bearing devices of muscles. A precise molecular picture of how sarcomeres are built underpins understanding their role in health and diseases. We determined the molecular architecture of native skeletal and cardiac sarcomeres and structures of sarcomeric p... |
 Wednesday, July 17th, 2024 - Seminar Speaker(s) : Jianping FU Bioengineering Human Embryo and Organ ModelsEarly human development remains mysterious and difficult to study. Recent advances in developmental biology, stem cell biology and bioengineering have contributed to a significant interest in constructing controllable, stem cell-based models of human embryo and organs (embryoids / organoids). T... |