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  • Tuesday, 10th, December 2019 - Séminaire Nuclear dynamic series Speaker(s) : Christian Lesterlin (Institut de Biologie et Chimie des Protéines)

    Real-time visualization of drug resistance acquisition by horizontal gene transfer reveals a new role for AcrAB-TolC multidrug efflux pump

    Drug resistance dissemination by horizontal gene transfer remains poorly understood at the cellular scale. Using live-cell microscopy, we reveal the dynamics of resistance acquisition by transfer of the F conjugative plasmid encoding the tetracycline-efflux pump TetA. We show that the entry of th...

  • Friday, 13th, December 2019 - Séminaire Speaker(s) : Amnon KOREN

    The Genetic and Epigenetic Basis of Human Genome Replication

    DNA replication follows a strict spatiotemporal program with a poorly understood genetic and epigenetic basis. To systematically uncover the genetic components of DNA replication timing regulation, we exploit inter-individual replication timing variation across human cells lines. In this talk, I ...

  • Tuesday, 17th, December 2019 - Séminaire Speaker(s) : Pavel MOZGUNOV (Dept. of Mathematics and Statistics)

    Adaptive and Response-Adaptive Clinical Trial Designs: Introduction and Recent Advances

    In this talk, I will tell about an emerging topic of the clinical trial design – adaptive designs. We will introduce what the adaptive design is, and consider its one of the most common variants – multi-arm multi-stage (MAMS) design, in which several treatments are compared to the com...

  • Tuesday, 17th, December 2019 - Séminaire Cell Biology Series Speaker(s) : Catherine RABOUILLE (Hubrecht Institute of the KNAW & UMC Utrecht, Nederland - Professor at Groningen University )

    GRASP65 and 55 and unconventional secretion in the gut

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  • Tuesday, 17th, December 2019 - Journée d'information

    Inscrivez-vous : prochaine réunion du Siège le 17 décembre 2019

    Pour la 5e fois, nous vous proposons de nous retrouver pour la réunion semestrielle de l'ensemble des collaborateurs du Siège qui se déroulera mardi 17 décembre 2019 de 9h30 à 14h dans le Bâtiment biologie du développement et cancer (Campus Curie) 11/13 rue Pierre-et-Marie-Curie.   Si vous ...

  • Thursday, 19th, December 2019 - Séminaire Speaker(s) : Enrico DALDELLO (Center for Reproductive Sciences, University of California – San Francisco)

    A switch in the translation program regulates meiotic maturation in mouse oocytes.

    Meiotic maturation is the final step of oogenesis when oocytes undergo two cell divisions without DNA replication to become haploid eggs. During this transition, de-novo accumulation of proteins and degradation of maternal mRNAs support progression through meiosis and render the egg competent for...

  • Wednesday, 15th, January 2020 - Séminaire Nuclear dynamic series Speaker(s) : Maria Rodríguez Martínez (IBM Zurich Research Laboratory)

    Artificial intelligence approaches for the analysis of single-cell proteomic (CyTOF) data in cancer

    The advances in high-throughput and single-cell technologies in biomedical research are generating an unprecedent amount of data that needs to be analyzed and integrated into their biological context. The team of Maria Rodríguez Martínez develops machine and deep-learning tools, together with sta...

  • Friday, 13th, March 2020 - Séminaire Speaker(s) : Mary GOLL

    Chromatin regulation in development and disease

    Assistant Professor, Department of Genetics University of Georgia

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