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  • Lundi 4 Septembre 2017 - Séminaire Immunology series Orateur(s) : Maria Rescigno (European Institute of Oncology and University of Milan, Italy)

    Interaction of the mucosal immune system with the microbiota

    The microbiota is emerging as an important environmental factor influencing several functions of our body. Many disorders have been associated to a disequilibrium of the microbiota that is called dysbiosis., these include not only gut disorders as inflammatory bowel disease and colorectal cancer,...

  • Lundi 11 Septembre 2017 - Séminaire Orateur(s) : Shane Crotty (La Jolla Institute for Allergy & Immunology (LJI), La Jolla, CA, USA)

    Assessing the engines of affinity maturation to vaccines: germinal centers and Tfh cells

    T cell help to B cells was one of the earliest discovered functions of T cells, 49 years ago, resulting in the coining of the term ‘helper cell'. Follicular helper T cells (Tfh) are the specialized CD4 T cells for B cell help. Generation of long term humoral immunity is a complex process pr...

  • Mardi 12 Septembre 2017 - Séminaire Orateur(s) : Philippe JAY (Institute of Functional Genomics, Montpellier)

    Tuft cells : intestinal epithelial sentinels linking luminal danger to immune responses

    - Gerbe F., Sidot E., Smyth D. J., Ohmoto M., Matsumoto I., Dardalhon V., Cesses P., Garnier L., Pouzolles M., Brulin B., Bruschi M., Harcus Y., Zimmermann V. S., Taylor N., Maizels R. M. and Jay P. : Intestinal epithelial tuft cells initiate type 2 mucosal responses to helminth parasites. Nature...

  • Jeudi 14 Septembre 2017 - Séminaire CDC Orateur(s) : Edgar GOMES (Institute of Molecular Medicine (IMM), Lisbon, Portugal)

    Positioning the nucleus for cell function

    Connecting the nucleus to the cytoskeleton is relevant for multiple cellular processes and disruption of these connections result in multiple pathologies. Nuclear positioning within cell cytoplasm requires de connection between nucleus and the cytoskeleton. We are interesting to understand the pr...

  • Lundi 18 Septembre 2017 - Symposium Orateur(s) : Symposium in memory of Dr. Ethel Moustacchi

    "DNA repair, Repair syndromes and Radiation biology" - Symposium in memory of Dr. Ethel Moustacchi

    Her name is undoubtedly linked to the Institut Curie that is why this symposium will take place in our premises. The symposium will cover the research themes to which Ethel Moustacchi dedicated her career. As she widely contributed to promote national and international prestigious institution s...

  • Vendredi 24 Novembre 2017 - Séminaire Orateur(s) : Sara Sigismund (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare)

    ER-PM contact sites control EGFR endocytosis and signaling

    The integration of distinct endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor (EGFR) is activated at high ligand concentrations, in parallel to clathrin-mediated endocytosis (CME). EGFR-NCE requires receptor...

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