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  • Mardi 21 Novembre 2017 - Séminaire CDC Orateur(s) : Gisou VAN DER GOOT

    Function and dynamics of a key post-translational modification, S-palmitoylation, with a focus on the ER

    Gisou van der Goot studied engineering at the Ecole Centrale de Paris, then did a PhD in Molecular Biophysics at the Nuclear Energy Research Center, Saclay, France, followed by a postdoc at the European Molecular Biology Laboratory (EMBL) in Heidelberg. She started her own group in 1994 in the de...

  • Mardi 21 Novembre 2017 - Séminaire Nuclear dynamic series Orateur(s) : Aurèle PIAZZA (Institut Pasteur)

    Multi-invasions-induced rearrangements: A molecular example of how hell can be paved with good intentions

    Inaccurate repair of broken chromosomes generates structural variants that can fuel evolution and inflict pathology. Homologous recombination (HR) seals DNA double strand breaks by using an intact donor molecule as a template for repair. As such it is considered a high fidelity repair mechanism. ...

  • Mercredi 22 Novembre 2017 - Séminaire Physico-Chimie Orateur(s) : Jean-Philippe Vert (ENS Paris - MINES ParisTech - Institut Curie)

    Machine learning for patient stratification from genomic data

    The possibility to collect genomic profiles (gene expression, mutations, …) from cancer patients paves the way to automatic patient stratification from genomic data to predict survival, risk of relapse or response to a therapy, for example. The stratification rule itself is usually estimat...

  • Du Lundi 20 Novembre 2017 Au Vendredi 24 Novembre 2017 - Cours international - séminaire

    7th Course on Development & Cancer: From Pigment Cell Development to Melanomas - 2017

    The course presents the current knowledge in neural crest and melanocytes development (cell biology, transcriptomics, imaging...) as well as how melanocytes undergo tumor progression in adults. It ends with presentation of the most up-to-date therapeutical strategies. Seminars are opened to In...

  • Vendredi 24 Novembre 2017 - Séminaire Orateur(s) : Sara Sigismund (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare)

    ER-PM contact sites control EGFR endocytosis and signaling

    The integration of distinct endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor (EGFR) is activated at high ligand concentrations, in parallel to clathrin-mediated endocytosis (CME). EGFR-NCE requires receptor...

  • Lundi 27 Novembre 2017 - Séminaire Curie TechWatch Orateur(s) : Gordon Hamilton

    Single-molecule genetic and epigenetic analysis of DNA and RNA using magnetic tweezers

    Depixus is a spin-out from the biophysics laboratory of Vincent Croquette, David Bensimon, and Jean-François Allemand at the École Normale Supérieure (ENS), Paris. The company is developing a novel technology called SIMDEQ (SIngle-molecule Magnetic DEtection & Quantification) for fast and accurat...

  • Mercredi 29 Novembre 2017 - Conférence

    From Nucleotides to Networks - The Real Transition to Precision Medicine

    Ximo DOPAZO, PhD, Director Clinical Bioinformatics,  Fundación Salud y Progreso - Andalusian Health Department , Spain Head of the Functional Genomics Note, Spanish National Bioinformatics Institute (INB)  

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Sylvie URBE

    DUB on the tracks: Linking deubiquitylase location and function

    Mammalian cells encode approximately hundred deubiquitylases (DUBs) that oppose the action of more than 400 E3-ligases. This imbalance has prompted the question whether, and if so how, selective substrate recognition can come about with such a relatively small cohort of enzymes. Although DUBs pla...

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Ron Vale (University of California, SAN FRANCISCO )

    RNA Aggregation in Neurodegenerative Disease

    RNA Aggregation in Neurodegenerative Disease

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Karin TARTE ( Faculté de médecine de Rennes / Service d'Immunologie, Thérapie Cellulaire et Hématopoïèse (ITeCH) - Pôle Cellules et Tissus)

    Lymphoma microenvironment: from good to evil

    Depuis son DEA, réalisé en 1995 à Montpellier, son parcours de recherche s'est toujours focalisé sur la compréhension des principales étapes de la différenciation des lymphocytes B matures normaux et sur la physiopathologie des néoplasies correspondantes. Elle a ainsi tout d'abord travaillé penda...

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