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  • Jeudi 19 Avril 2018 - Séminaire Orateur(s) : Alexander AULEHLA (EMBL, Heidelberg)

    Origin and function of synchronized signaling oscillations during embryonic patterning

    Abstract: We study the role of signaling dynamics during embryonic development and hence investigate the function of embryonic clocks, or oscillators. Ultradian oscillations (period ~2 hours) in Wnt, Fgf and Notch signaling pathway activity have been identified in mouse embryos and are linked to ...

  • Vendredi 20 Avril 2018 - Séminaire Orateur(s) : Dr. Nevan Krogan (Director, QBI - Quantitative Biosciences Institute University of California, San Francisco)

    The Cancer Cell Map Initiative: Using Network Biology to Interpret Cancer Genomic Data

    Progress in DNA sequencing has revealed the startling complexity of cancer genomes, which typically carry thousands of somatic mutations. However, it remains unclear which are the key driver mutations or dependencies in a given cancer and how these influence pathogenesis and response to therapy. ...

  • Vendredi 20 Avril 2018 - Séminaire Orateur(s) : Eran MESHORER (The Hebrew University of Jerusalem ISRAEL)

    Epigenetics : From pluripotent stem cells to ancient DNA

    The Meshorer lab is studying nuclear processes in embryonic and neuronal stem cells, as well as in pluripotent models of neurodegenerative diseases, including chromatin dynamics and structure, nuclear architecture, transcription and splicing as well as epigenetic processes, in attempt to understa...

  • Mardi 24 Avril 2018 - Séminaire Cell Biology Series Orateur(s) : Cyril HANUS

    High prevalence of unconventional secretory processing in neurons and its impact on the glycosylation and function of the neuronal surface


  • Mardi 24 Avril 2018 - Séminaire

    Publishing Your Work: A Cell Editor’s Perspective

    Elena Porro is Senior Deputy Editor of Cell and Editorial Director at Cell Press. Since joining Cell Press in 2000, Elena has also served as an editor of Molecular Cell, Developmental Cell, and Neuron. At Cell she is responsible for the daily operations of the journal, managing the editorial team...

  • Mardi 24 Avril 2018 - Séminaire Orsay series Orateur(s) : Sandra Demaria (Department of Radiation Oncology and Pathology and laboratory medicine, Weill Cornell Medicine, New York, NY.)

    Mechanisms of radiation-induced tumor immunogenicity

    Most cancer cells exposed to ionizing radiation do not undergo immediate death even when the damage is lethal but remain within the tumour mass for some time during which they generate molecular signals that modify the cross-talk of the tumour with the host immune system. Central to this process ...

  • Mercredi 25 Avril 2018 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Madalena Tarsounas (Genome Stability and Tumourigenesis Group, The CR-UK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, U.K.)

    WNT/beta-catenin signaling in BRCA-deficient cells

    WNT/beta-catenin signaling plays key roles in normal tissue development and homeostasis, where it controls cell proliferation, differentiation and apoptosis. Deregulation of this pathway is associated with cancer progression or inhibition, depending on the genetic context. Glycogen synthase kinas...

  • Jeudi 3 Mai 2018 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Rebecca OAKEY (King's College, London, UK)

    Imprinted loci as a model for studying epigenetic regulation of alternative polyadenylation


  • Jeudi 3 Mai 2018 - Séminaire Orateur(s) : Jérôme LARGHERO (Hôpital Saint-Louis, Paris)

    Updates on cellular therapy and tissue engineering taking place at St Louis Hospital

    Jerome Larghero qui dirige la plateforme de thérapie cellulaire de l'Hôpital St Louis - Médicaments de Thérapie Innovante (MTI) nous parlera ses activités de thérapie cellulaire (dont cellules CAR-T) et d'ingénierie tissulaire à l'Hôpital St Louis.

  • Mardi 15 Mai 2018 - Séminaire Cell Biology Series Orateur(s) : Alexander DAMMERMANN

    Defining Centriole Function in Centrosome And Cilium Biogenesis


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