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  • Friday, 20th, September 2019 - Séminaire Speaker(s) : Florence Le Calvez-Kelm (International Agency for Research on Cancer (IARC), Lyon)

    Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer

    Dr Florence Le Calvez-Kelm is a senior scientist in the Genetic Cancer Susceptibility group at the International Agency for Research on Cancer (IARC), Lyon. She is leading the Agency-wide Genomics platform and coordinates collaborative genomic projects within IARC and outside. She is currently co...

  • Friday, 20th, September 2019 - Séminaire Speaker(s) : Stephen KOWALCZYKOWSKI (University of California, Department of Microbiology and Molecular Genetics, Department of Molecular and Cellular Biology, Davis, USA, Chaires Blaise Pascal, Région Ile de France)

    Watching DNA Recombination and Replication, One Molecule at a Time: Understanding Biology from Stochastic Behavior

    Watching DNA Recombination and Replication, One Molecule at a Time: Understanding Biology from Stochastic Behavior

  • Tuesday, 24th, September 2019 - Séminaire Cell Biology Series Speaker(s) : Helfrid HOCHEGGER

    Triggering mitosis

    Dr Hochegger is a Reader in Genome Stability and heads the cell cycle control lab at the GDSC investigating how human cells enter mitosis and how this process has been changed in cancer.

  • Wednesday, 25th, September 2019 - Séminaire Orsay series Speaker(s) : Eyal Gottlieb (The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel)

    Targeting Cancer's metabolic vulnerabilities

    Much have changed over the past decade in the way we perceive metabolism in cancer research and cancer clinical management. Several routes have led to this conceptual transformation, including technological achievements, genetic observations, diagnostic tools and pharmacological approaches. These...

  • Thursday, 26th, September 2019 - Séminaire Speaker(s) : Kim JENSEN

    At the origin of intestinal epithelial stem cells and beyond

    Normal adult intestinal stem cells (ISCs) are located within stem cells niches, where the number of stem cells, proliferation within the stem cell compartment and potentially their future cell fate is controlled by niche factors. ISCs are sufficient for life-long replenishment of intestinal epith...

  • Friday, 27th, September 2019 - Séminaire Speaker(s) : Sylvie Urbé (Institute of Translational Medicine, University of Liverpool, Liverpool, UK)

    Deubiquitylases (DUBs) : druggable regulators of protein and organelle homeostasis

    More information to come 

  • Friday, 27th, September 2019 - Séminaire institutionnel "Marie Curie Seminar" Speaker(s) : Peter KHARCHENKO (Harvard Medical School Boston, MA, USA)

    Integrative Analysis of large single-cell RNA-seq collections

    Integrative Analysis of Large Single-Cell RNA-Seq Collections Peter Kharchenko Harvard Medical School Abstract: Single-cell RNA-seq methods are being increasingly applied in complex study designs, which involve measurements of many samples, commonly spanning multiple individuals, cond...

  • Monday, 30th, September 2019 - Séminaire institutionnel "Mayent - Rothschild" Speaker(s) : David GOLDGAR (Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicines)

    Leveraging large clinical testing data sets to make inferences about pathogenicity of observed genetic variants

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  • Monday, 30th, September 2019 - Séminaire Speaker(s) : Cécile Alanio (Wherry lab, Institute for Immunology, Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, USA)

    T cell trafficking defect in pancreatic cancer

    T cells engineered to express chimeric antigen receptors (CARs) have established efficacy in the treatment of B-cell malignancies, but their relevance in solid tumors remains undefined. As part of the Su2C CAR T translational team, together with Carl June and Shelley Berger, we are working to dev...

  • Tuesday, 1st, October 2019 - Séminaire Cell Biology Series Speaker(s) : Jean-Sébastien HOFFMANN

    DNA polymerase theta in cancer risk and therapy

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