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  • Tuesday, 18th, January 2022 - Séminaire Nuclear dynamic series Speaker(s) : Jakub Wiktor ( Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden)

    The reduced-dimensionality mechanism of homology search by RecA filament during double stranded break repair

    Homologous recombination is essential for the accurate repair of double-stranded DNA breaks (DSBs). Initially, the RecBCD complex resects the ends of the DSB into 3′ single-stranded DNA on which a RecA filament assembles. Next, the filament locates the homologous repair template on the sist...

  • Tuesday, 18th, January 2022 - Mini-colloquium Speaker(s) : ,

    Introduction to the Technological Platforms of the Research Centre (“mode d’emploi”) - CurieCoreTech

    An introduction to the Technological Platforms of the Research Centre « Mode d'emploi plateformes » Please join us online for presentations from the technological platforms of the Research Centre of Institut Curie – CurieCoreTech Tuesday 18th of January 2022 from 13:40 – 1...

  • Wednesday, 19th, January 2022 - Séminaire Physico-Chimie Speaker(s) : Leif Dehmelt (TU Dortmund University and Max Planck Institute of Molecular Physiology)

    Spatio-temporal organization of morphogenic signal network dynamics in cells

    Cells have to dynamically and locally change their shape to perform various physiological functions. For example, during directional migration, cells generate protrusive forces in their front and contractile forces in their back. How cells control such local cell shape changes is still poorly und...

  • Thursday, 20th, January 2022 - Séminaire Physico-Chimie Speaker(s) : Gaspard Junot (Department of Condensed Matter Physics, University of Barcelona)

    Transport and dynamics of E.coli bacteria at the microscale

    Understanding the properties of bacterial suspension is crucial for both applications and fundamental purposes. In this seminar, I will talk about the transport properties of Escherichia Coli bacteria in suspension. To probe those properties I used a 3D lagrangian tracking device able to follow b...

  • Friday, 21st, January 2022 - Séminaire Speaker(s) : Pieter Mestdagh (the Cancer Research Institute Ghent (CRIG))

    The role of lncRNAs in cancer

    The human genome is pervasively transcribed, producing a highly complex transcriptome including thousands of so-called long non-coding RNAs (lncRNAs). Expression of these lncRNAs is deregulated in virtually all cancer types and mechanistic studies suggest they act as regulators of various biologi...

  • Friday, 28th, January 2022 - Séminaire Initiative Single Cell Speaker(s) : Nina Radosevic-Robin (Department of Pathology, Centre Jean Perrin & University Clermont Auvergne / INSERM U1240)

    GeoMx® Digital Spatial Profiler by NanoString Technology: Application in cancer research and the first experiences of the Centre Jean Perrin team

    GeoMx® Digital Spatial Profiler (DSP), launched by NanoString Technology (NST) in 2019, is a powerful instrument for high-plex, high-throughput in situ analysis of gene or protein expression. The DSP is currently capable of assessing the whole human or mouse transcriptome (18000+ protein-coding g...

  • Tuesday, 1st, February 2022 - Séminaire Labex Speaker(s) : Ewa Paluch

    Cross-talk between cell mechanics, cell shape and cell fate

    A precise control of cell morphology is key for cell physiology, and cell shape deregulation is at the heart of many pathological disorders, including cancer. Cell morphology is intrinsically controlled by mechanical forces acting on the cell surface, to understand shape it is thus essential to i...

  • Wednesday, 2nd, February 2022 - Séminaire Speaker(s) : Marcus Conrad

    Ferroptosis: From basic mechanisms to therapeutic opportunities

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  • From Monday, 14th, February 2022 To Friday, 18th, February 2022 - Cours international - séminaire

    Cours sur l'instabilité des génomes & pathologies humaines (14-18 fev.)

    L'instabilité génétique est une caractéristique des cellules cancéreuses mais aussi une cause de maladies génétiques chez l'homme. Notre appréhension des relations causales entre instabilité génétique et le développement de pathologies humaines repose sur nos connaissances des mécanismes fondamen...

  • Tuesday, 22nd, February 2022 - Séminaire Speaker(s) : Helge Ewers

    Controlled ligand affinity and avidity for lipid-mediated endocytosis.

    Controlled ligand affinity and avidity for lipid-mediated endocytosis.

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