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  • Vendredi 24 Novembre 2017 - Séminaire institutionnel "Marie Curie Seminar" Orateur(s) : Robert A. Martienssen (Cold Spring Harbor Laboratory, New York - USA)

    Small interfering RNA in replication, recombination and repair

    Rob Martienssen is investigating the role of heterochromatin reprogramming and RNA interference in plant germ cells. These mechanisms reveal and regulate transposable elements, but they also play important roles in meiosis and reproductive fate.

  • Vendredi 24 Novembre 2017 - Séminaire Orateur(s) : Sara Sigismund (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare)

    ER-PM contact sites control EGFR endocytosis and signaling

    The integration of distinct endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor (EGFR) is activated at high ligand concentrations, in parallel to clathrin-mediated endocytosis (CME). EGFR-NCE requires receptor...

  • Lundi 27 Novembre 2017 - Séminaire Curie TechWatch Orateur(s) : Gordon Hamilton

    Single-molecule genetic and epigenetic analysis of DNA and RNA using magnetic tweezers

    Depixus is a spin-out from the biophysics laboratory of Vincent Croquette, David Bensimon, and Jean-François Allemand at the École Normale Supérieure (ENS), Paris. The company is developing a novel technology called SIMDEQ (SIngle-molecule Magnetic DEtection & Quantification) for fast and accurat...

  • Mercredi 29 Novembre 2017 - Conférence

    From Nucleotides to Networks - The Real Transition to Precision Medicine

    Ximo DOPAZO, PhD, Director Clinical Bioinformatics,  Fundación Salud y Progreso - Andalusian Health Department , Spain Head of the Functional Genomics Note, Spanish National Bioinformatics Institute (INB)  

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Sylvie URBE

    DUB on the tracks: Linking deubiquitylase location and function

    Mammalian cells encode approximately hundred deubiquitylases (DUBs) that oppose the action of more than 400 E3-ligases. This imbalance has prompted the question whether, and if so how, selective substrate recognition can come about with such a relatively small cohort of enzymes. Although DUBs pla...

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Ron Vale (University of California, SAN FRANCISCO )

    Ron Vale - RNA Aggregation in Neurodegenerative Disease

    RNA Aggregation in Neurodegenerative Disease

  • Mercredi 29 Novembre 2017 - Séminaire Orateur(s) : Karin TARTE ( Faculté de médecine de Rennes / Service d'Immunologie, Thérapie Cellulaire et Hématopoïèse (ITeCH) - Pôle Cellules et Tissus)

    Lymphoma microenvironment: from good to evil

    Depuis son DEA, réalisé en 1995 à Montpellier, son parcours de recherche s'est toujours focalisé sur la compréhension des principales étapes de la différenciation des lymphocytes B matures normaux et sur la physiopathologie des néoplasies correspondantes. Elle a ainsi tout d'abord travaillé penda...

  • Jeudi 30 Novembre 2017 - Séminaire Physico-Chimie Orateur(s) : Ido AMIT (Weizmann Institute of Science, Rehovot, Israel )

    The power of ONE: Immunology in the age of single cell genomics

    The immune system is a complex, dynamic and plastic network composed of various interacting cell types that are constantly sensing and responding to environmental cues. From very early on, the immunology field has invested great efforts and ingenuity to characterize the various immune cell types ...

  • Vendredi 1 Décembre 2017 - Séminaire Physico-Chimie Orateur(s) : Eugenia PIDDINI (School of Cellular and Molecular Medicine, Faculty of Biomedical Sciences, University of Bristol, UK)

    p53 and Mechanical Cell Competition: mechanisms and role in collective cell migration and wound healing

    My group studies the mechanisms and function of cell competition in health and disease. Cell competition is a fundamental phenomenon that allows fitter cells (called ‘winners') to kill less fit cells (called ‘losers') and colonize tissues in their stead. The goal of my research is to ...

  • Vendredi 1 Décembre 2017 - Séminaire Orateur(s) : Sander van den Heuvel (IBB, Utrecht University)

    Asymmetric cell division, differentiation, and a dosage-dependent tumor suppressor function for SWI/SNF chromatin remodelers

    Animal development and tissue maintenance depend on the generation of specialized cells at the right place and in the proper numbers. Defects in these processes underlie developmental abnormalities and cancer formation. We use the nematode Caenorhabditis elegans to study developmental control of ...

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