Seminars list
Stroma-Macrophage Two Cell CircuitsMacrophages sustain tissue homeostasis within the body through trophic, regulatory and repair functions. Macrophage homeostasis is locally regulated by “niches." Although this concept has recently found great appreciation in the field, the very nature of these niches and the molecular dialo... |
 Wednesday, May 12th, 2021 - Physical Chemistry Seminar Speaker(s) : Anton Goloborodko (IMBA Vienna, Austria) Unraveling the structure of paired homologs and sister chromatids with Hi-C and polymer modelingThe genomes of living organisms are stored on DNA molecules, called chromosomes, which are typically present in multiple copies. For example, diploid organisms have two slightly different copies of each chromosome, called homologs. Moreover, in preparation for division, cells duplicate their chro... |
 Wednesday, May 19th, 2021 - Physical Chemistry Seminar Speaker(s) : Sophie Brasselet (Institut Fresnel, Marseille) Super resolution imaging of proteins organization in 3D using polarized single molecule localizationImaging molecular orientation at the nanoscale in live cells and tissues is fundamental in the understanding of proteins' organization, which is driven by their structural and conformational properties. Measuring fluorescent molecules' orientation is an interesting way to approach this problem, p... |
Enter the matrix: modeling tumor cell and immune cell interactions at the single cell resolutionTumors employ complex, multi-scale cellular and molecular interactions that evolve over the course of therapeutic response. The changes in these pathways enables tumors to overcome therapeutic regimens, and ultimately acquire resistance. New molecular profiling technologies, including notably sin... |
STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcomaSTAG2, a cohesin family gene, is among the most recurrently mutated genes in cancer. STAG2 loss-of-function (LOF) is associated with aggressive behavior in Ewing sarcoma, a childhood cancer driven by aberrant transcription induced by the EWSR1-FLI1 fusion oncogene. Here, using isogenic Ewing cell... |
 Tuesday, May 25th, 2021 - Webinar Register now for the "ADAPT to Thrive" virtual event on failure and resilience!University College London, UMC Utrecht and Institut Curie are partnering to host a virtual event on 25 May as part of the ADAPT to Thrive event series on failure and resilience. Would you like to hear how accomplished academics and research leaders failed and lived to tell the story? Get advic... |
Epigene2sys online meeting 2021Epigene2Sys is a CNRS GDRi, coordinated by G. Almouzni (CNRS, Paris) and M-E Torres Padilla (HGMU, Munich), was launched in 2018 in continuation to the EpiGeneSys Network of Excellence, with the aim to stimulate discoveries and discussions in epigenetics research and to encourage equal opportuni... |