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  • Monday, September 4th, 2017 - Seminar Immunology series Speaker(s) : Maria Rescigno (European Institute of Oncology and University of Milan, Italy)

    Interaction of the mucosal immune system with the microbiota

    The microbiota is emerging as an important environmental factor influencing several functions of our body. Many disorders have been associated to a disequilibrium of the microbiota that is called dysbiosis., these include not only gut disorders as inflammatory bowel disease and colorectal cancer,...

  • Monday, September 4th, 2017 - Seminar Speaker(s) : Max Gottesman MD PhD (Columbia University, New York, USA)

    Coupling and Uncoupling Transcription with Translation

    We show that transcription and translation are physically coupled in E.coli by the NusG protein. The NTD of NusG binds RNAP, whereas its CTD binds ribosomal protein S10. We present a cryo-EM structure showing NusG CTD bound to S10 in an intact 70S ribosome. We find that NusG is required for coupl...

  • Tuesday, September 5th, 2017 - Seminar Nuclear dynamic series Speaker(s) : Abby DERNBURG (Department of >Molecular & Cell Biology, University of California, Berkeley (CA, USA))

    A liquid crystalline interface between chromosomes controls meiotic recombination

    Dr. Dernburg's lab is interested in meiosis, the special division process by which the genetic information on chromosomes is transmitted from parent to progeny through sexual reproduction. Errors in this process lead to aneuploidy and are a major cause of human birth defects such as Down syndrome...

  • Monday, September 11th, 2017 - Seminar Speaker(s) : Shane Crotty (La Jolla Institute for Allergy & Immunology (LJI), La Jolla, CA, USA)

    Assessing the engines of affinity maturation to vaccines: germinal centers and Tfh cells

    T cell help to B cells was one of the earliest discovered functions of T cells, 49 years ago, resulting in the coining of the term ‘helper cell'. Follicular helper T cells (Tfh) are the specialized CD4 T cells for B cell help. Generation of long term humoral immunity is a complex process pr...

  • Monday, September 11th, 2017 - Institutional seminar "Mayent - Rothschild" Speaker(s) : Yves Pommier (Center for Cancer Research, National Cancer Institute, NIH)

    Precision Medicine and DNA-Targeted Agents

          

  • Tuesday, September 12th, 2017 - Seminar Speaker(s) : Philippe JAY (Institute of Functional Genomics, Montpellier)

    Tuft cells : intestinal epithelial sentinels linking luminal danger to immune responses

    - Gerbe F., Sidot E., Smyth D. J., Ohmoto M., Matsumoto I., Dardalhon V., Cesses P., Garnier L., Pouzolles M., Brulin B., Bruschi M., Harcus Y., Zimmermann V. S., Taylor N., Maizels R. M. and Jay P. : Intestinal epithelial tuft cells initiate type 2 mucosal responses to helminth parasites. Nature...

  • Thursday, September 14th, 2017 - CDC Seminar Speaker(s) : Edgar GOMES (Institute of Molecular Medicine (IMM), Lisbon, Portugal)

    Positioning the nucleus for cell function

    Connecting the nucleus to the cytoskeleton is relevant for multiple cellular processes and disruption of these connections result in multiple pathologies. Nuclear positioning within cell cytoplasm requires de connection between nucleus and the cytoskeleton. We are interesting to understand the pr...

  • Thursday, September 14th, 2017 - Seminar Speaker(s) : Patrick Rochette (Centre de Recherche du CHU de Québec – Université Laval, Québec, Canada)

    Ultraviolet A-induced oxidation in the cornea: short and long-term effects

    Human eye is directly exposed to solar ultraviolet (UV) radiations but the retina is protected from those rays. Indeed, the cornea and the lens filter UV rays to protect the retina against their toxicity. The UVA component represents 95% of solar UV radiation and has photo-oxidant properties. How...

  • Monday, September 18th, 2017 - Symposium Speaker(s) : Symposium in memory of Dr. Ethel Moustacchi

    "DNA repair, Repair syndromes and Radiation biology" - Symposium in memory of Dr. Ethel Moustacchi

    The symposium DNA repair, Repair syndromes and Radiation Biology is a tribute to the memory of Ethel Moustacchi. Her name is undoubtedly linked to the Institut Curie that is why this symposium will take place in our premises. The symposium will cover the research themes to which Ethel Moustac...

  • Tuesday, September 19th, 2017 - Seminar Speaker(s) : Carolyn J. BROWN (Department of Medical Genetics, University of British Columbia)

    Making two equal one: Human X-chromosome inactivation

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