Seminars list
 Monday, May 11th, 2020 - Seminar Speaker(s) : Jean-Pierre Quivy (Institut Curie), Leticia Niborski (Institut Curie) EpiProMeS seminar: heterochromatin and cancerDr. Jean-Pierre Quivy (Institut Curie UMR3664 – G. Almouzni team “Chromatin Dynamics”) will present an ongoing project in which a marker of centromeric chromatin was found to be highly predictive for response to radio-chemotherapy in head and neck cancer. To be confirmed: Dr.... |
Growth response to compression: how conserved rheological properties may set a universal response.Any cell population growing in confinement can experience a growth-induced compressive stress, from bacteria to animal cells. We observe in the budding yeast S. cerevisiae that growth decreases under pressure, and that this decrease does not seem to depend on specific mechanosensors. Using novel ... |
Real-time visualization of drug resistance acquisition by horizontal gene transfer reveals a new role for AcrAB-TolC multidrug efflux pumpDrug resistance dissemination by horizontal gene transfer remains poorly understood at the cellular scale. Using live-cell microscopy, we reveal the dynamics of resistance acquisition by transfer of the F conjugative plasmid encoding the tetracycline-efflux pump TetA. We show that the entry of th... |
Illuminating Genome Organization through Integrated Microscopy and SequencingIn human cells, two meters of DNA sequence are compressed into a nucleus whose linear size is five orders of magnitude smaller. Deciphering how this amazing structural organization is achieved and how DNA functions can ensue in the environment of a cell's nucleus represent central questions for c... |