Seminars list
Unraveling Cancer Metabolism by Next-Generation MetabolomicsReprogramming of cell metabolism, including aerobic glycolysis, also known as the Warburg effect, has been increasingly acknowledged as one of the ten hallmarks of cancer. Therefore, metabolomics is an ideal tool for a systemic analysis of the metabolic phenotype of cancer patients, the discovery... |
The generation of neural diversityThe Drosophila optic lobes receive retinotopic inputs from photoreceptors and over 100 types of neurons in the optic lobes process these inputs for extracting visual information. They are organized in 800 columns corresponding to the 800 unit eyes in the retina (ommatidia). How is this variety of... |
Domain 2 MeetingAgenda to come. |
Daddy issues: effects of the paternal environment on the next generation in mammalsOllie and his team have recently described that mammalian spermatozoa are loaded with small RNA fragments during their journey through the reproductive tract, which impact phenotypes when transmitted to the next generation. He is also a great specialist in chromatin and nuclear organization i... |
Daddy issues: effects of the paternal environment on the next generation in mammalsOllie and his team have recently described that mammalian spermatozoa are loaded with small RNA fragments during their journey through the reproductive tract, which impact phenotypes when transmitted to the next generation. He is also a great specialist in chromatin and nuclear organization i... |
Regulation of genomic imprinting in development and diseaseRegulation of genomic imprinting in development and disease |
 Monday, May 13th, 2019 - Seminar Immunology series Speaker(s) : Greg Towers (University College London - Division of Infection and Immunity, London UK) Catch me if you can: HIV Capsid and evasion of innate immunity is associated with human pandemicityLike all viruses, lentiviruses must navigate the hostile environment of the host cell in order to infect, produce new viral particles, and transmit to new cells. A principal component of cellular defences is detection or sensing of incoming viruses and subsequent production of inflammatory cytoki... |
Li-Fraumeni Syndrome: What are the challenges and opportunities 50 years after the first report?More than 85% of patients with Li-Fraumeni syndrome harbour germline TP53 mutations. The spectrum of mutations and the heterogeneity of tumor presentation (age of onset and type) within and between families is remarkable, and indicates that modifiers must play an important role in defining the ph... |
Forcing the nuclear envelope to respond: From nuclear deformation to cell cycle progressionWhether it is generated by myosin motors or externally applied, cells are constantly subjected to mechanical tension, which profoundly impacts their growth. Mechanical tension triggers changes in cell shape, adhesion and cytoskeletal structures that control the cell-cycle machinery and orchestrat... |
The Quest to Unravel the Complex Biology of Glioblastoma: from Genomics and BeyondGlioblastomas (GBMs) are the most frequent and aggressive primary tumors in the central nervous system owing to their fast clinical course and uniform lethality In the past decade, there has been a big step forward in the identification of the genomic and epigenomic alterations found in GBM pa... |