Liste des séminaires
 Lundi 13 Mai 2024 - Séminaire Orateur(s) : Jeroen Roose (University of California, San Francisco) Deconstruct-Reconstruct Decode cancer-immune crosstalk & probe with organoids.The Roose team at UCSF studies mechanisms of cell-cell interactions in immunology and cancer1-7, with emphasis on personalized medicine4,8 and single cell approaches9-11. Over the past 7 years, we shifted a large portion of our research efforts to understanding human biology and disease. We are d... |
How do single bacterial cells think?The functioning of genome-wide gene regulatory networks in bacteria presents us with an apparent paradox. On the one hand, bacterial populations successfully coordinate their gene expression patterns and phenotypes to allow them to grow in a huge variety of environments, including complex combina... |
Contrôle de la taille des cellulesLa taille des cellules joue un rôle crucial dans le fonctionnement de divers types de cellules dans tout le corps humain, influençant la structure des organites, la biosynthèse et les processus de transport en surface. Bien que certains gènes influençant la taille des cellules aient été identifié... |
 Mardi 21 Mai 2024 - Séminaire Orateur(s) : Hironori Funabiki (The Rockefeller University, New York) Nucleosomes and DNA methylation implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancersDNA methylation is a broadly observed epigenetic modification. As genomic DNA methylation profiles dynamically change during development and aging, alterations in DNA methylation patterns are linked to diseases such as cancers and immunodeficiency. ICF syndrome is characterized by hypomethylation... |
 Mercredi 29 Mai 2024 - Séminaire Orateur(s) : Pierre Ronceray Learning dynamical models from stochastic trajectoriesThe dynamics of biological systems, from proteins to cells to organisms, is complex and stochastic. To decipher their physical laws, we need to bridge between experimental observations and theoretical modeling. Thanks to progress in microscopy and tracking, there is today an abundance of experime... |
 Du Mercredi 22 Mai 2024 Au Mercredi 29 Mai 2024 - Cours international - séminaire Génome non-codantLe cours « NON-CODING GENOME » explorera la diversité des éléments d'ADN non géniques et des ARN non codants dans un large spectre de processus cellulaires, chez l'homme et les organismes modèles, ainsi que leur implication dans la physiologie et la pathologie. Des experts de renommée internation... |
Coping with mechanical stress: tissue dynamics during development, homeostasis and repair.Abstract: During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maint... |
 Vendredi 31 Mai 2024 - Séminaire Orateur(s) : Wei Yang (National Institute of Health - NIH) Cutting and Pasting DNA to Create our Adaptive Immune SystemV(D)J recombination is essential for generating the adaptive immune response and unlimited number of different antibodies and antigen receptors. Encoded by multiple V, D and J gene segments, antigen receptors are assembled by programmed double-stranded DNA cleavage and imprecise re-joining. RAG1/... |
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTIONIn the Drosophila optic lobes, ~200 types of neurons organized as 800 columns process the inputs from 800 unit-eyes. We study how this variety of neurons is generated during development and how connectivity among these neurons is regulated The ~800 Neural stem cells in the medulla ... |
Structures in situ des sarcomères musculaires et des protéines sarcomèresLes sarcomères sont des dispositifs musculaires générateurs de force et porteurs de charge. Une image moléculaire précise de la façon dont les sarcomères sont construits permet de comprendre leur rôle dans la santé et les maladies. Nous avons déterminé l'architecture moléculaire des sarcomères sq... |