Seminars list
Protect and recycle: how cells regulate dormancyOur research is focused on elucidating how cell growth and division are regulated in space and time, in particular by selective degradation of cellular components. Eukaryotic cells use autophagy and the ubiquitin-​proteasome system (UPS) to ensure cellular homeostasis, and recycle excess an... |
Cell Size ControlCell size plays a crucial role in the function of various cell types throughout the human body, influencing organelle structure, biosynthesis, and surface transport processes. Although certain genes influencing cell size have been identified, the molecular mechanisms by which cell growth initiate... |
In situ structures of muscle sarcomere and sarcomeric proteinsSarcomeres are force-generating and load-bearing devices of muscles. A precise molecular picture of how sarcomeres are built underpins understanding their role in health and diseases. We determined the molecular architecture of native skeletal and cardiac sarcomeres and structures of sarcomeric p... |