Seminars list
 Tuesday, September 3rd, 2024 - Institutional seminar "Mayent - Rothschild" Speaker(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem) Pluripotent stem cell models reveal altered genetic and epigenetic pathways in Huntingtons diseaseI will discuss juvenile and infantile forms of human pluripotent stem cell (hPSC) isogenic models for Huntington's disease (HD), the most common poly-glutamine (polyQ) related disorder. HD is caused by CAG (encoding glutamine, Q) expansions within the Huntingtin (HTT) gene. The aberrant polyQ-con... |
 Monday, September 16th, 2024 - Institutional seminar "Mayent - Rothschild" Speaker(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem) Epigenetics: from human pluripotent stem cell models of neurodegenerative diseases to recent human evolutionIn the first part, I will discuss juvenile and infantile forms of human pluripotent stem cell (hPSC) isogenic models for Huntington's disease (HD), the most common poly-glutamine (polyQ) related disorder. HD is caused by CAG (encoding glutamine, Q) expansions within the Huntingtin (HTT) gene. The... |
 Tuesday, October 8th, 2024 - Institutional seminar "Mayent - Rothschild" Speaker(s) : Eran Meshorer (Department of Genetics, The Institute of Life Science & The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem) Epigenetics: from pluripotent stem cells to ancient DNAPluripotent embryonic stem cells (ESCs) are characterized by a unique, globally decondensed, chromatin structure. In the first and main part will describe our endogenously-tagged fluorescent-fusion protein libraries in mouse ESCs, which we used to screen for potential regulators of pluripotency a... |