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  • Vendredi 14 Décembre 2018 - Séminaire Immunology series Orateur(s) : Andrey Shaw (Immunology-Oncology Department, Genentech (USA))

    The role of CD2AP in myeloid cells

    We originally cloned CD2AP as an adaptor protein involved in immunological synapse formation in T lymphocytes.  However, the CD2AP knockout mouse, dies of nephrotic syndrome (kidney) and mutations in CD2AP are a risk factor for Alzheimer's disease.  In addition, CD2AP is most highly expressed in ...

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