Targeting genes for repression: lessons from old and new model species
Cell identities are largely defined by their transcriptomes, which result from precise gene activation and silencing programs. In this context, a major and still unresolved question is how particular genes are targeted for repression in certain cell types while they are expressed in others. Here, I will discuss how classic and emerging model species (Drosophila, mice and crickets) deal with this central issue, highlighting common trends but also divergent features, putting into perspective the conservation of these mechanisms.
Épigénétique de la Régénération et du Cancer
Institute of Advanced Biosciences, Grenoble University
Dynamique de l'information génétique : bases fondamentales et cancer (DIG-Cancer) (UMR3244)
Seminar suggested by Céline Vallot