Liste des séminaires
A Miniaturized Light-Sheet Microscopy for Whole-Brain Calcium Imaging during Physiological Vestibular Stimulation in Larval ZebrafishThe vestibular apparatus provides animals with postural and movement-related information that is essential to adequately execute numerous sensorimotor tasks. In order to activate this sensory system in a physiological manner, one needs to macroscopically rotate or translate the animal's head, whi... |
 Jeudi 21 Février 2019 - Séminaire Orateur(s) : Masaru Ishii (Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Osaka, Japan) Dynamics of immune cell migration and interaction visualized by intravital microscopyDuring the last decade, intravital optical microscopy has launched a new trend in the field of biology. By using this advanced imaging technique we have established a new system for visualizing in situ behavior of a diversity of living cells within intact tissues and organs. Among them, we succee... |
PARP Inhibitor Resistance and Acquired VulnerabilityLarge-scale genomic studies have demonstrated that approximately 50% of high-grade serous ovarian cancers (HGSOCs) harbor genetic and epigenetic alterations in homologous recombination repair (HRR) pathway genes. The most commonly altered HRR genes are BRCA1 and BRCA2, followed by other Fanconi A... |
Computational methods for fluorescence microscopy and cryo-electron tomographyComputational methods for fluorescence microscopy and cryo-electron tomography Charles Kervrann Serpico Team / Inria - CNRS - Institut Curie - UPMC During the past two decades, biological imaging has undergone a revolution in the development of new light and electron microscopy techniques that al... |
Presence, function and targeting of G-quadruplexes in the human immunodeficiency virus-1 (HIV-1)Presence, function and targeting of G-quadruplexes in the human immunodeficiency virus-1 (HIV-1) |
Amir Bitran : Rare codons coordinate co-translational protein folding to avoid misfolded intermediatesIn the cell, many proteins begin folding co-translationally. To ensure proper function, co-translational folding must allow proteins to rapidly reach their native state while avoiding potentially harmful misfolded intermediates. Here we provide evidence that this process may be regulated in vivo ... |
Engineering genomes, karyotypes, and the dark matter of the human genomeRapid advances in DNA synthesis techniques have made it possible to engineer diverse genomic elements, pathways, and whole genomes, providing new insights into design and analysis of systems. The synthetic yeast genome project, Sc2.0 is well on its way with seven synthetic Saccharomyces cerevisia... |
 Lundi 11 Mars 2019 - Séminaire Orateur(s) : Carlos Salomon (Head of the Exosomes Biology Laboratory, University of Queensland Centre for Clinical Research, Brisbane - Australia) Extracellular vesicles in Obstetrics and Gynaecology: Focus on pregnancy complications and ovarian cancerI am a group leader and senior Lions Medical Research Foundation (LMRF) Fellow working at the University of Queensland Centre for Clinical Research (UQCCR). I am recognized as a national and international researcher working in the field of extracellular vesicles focusing on the reproductive biolo... |
Exploring mRNA translation as a target in cancerI will discuss recent insights into new therapeutic targets in cancer with an emphasis on lymphoma/leukemia. These will include mRNA translation, immune-receptors and unpublished data from genetic CRISPR/CAS9 screens for new and druggable mechanisms |
Domain 2 Seminar - Linda PartridgeTitle & abstract to come. |