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  • Mardi 19 Mars 2024 - Séminaire Orateur(s) : Ivaylo Ivanov (Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University)

    Microbiota-immune interactions in health and disease

    Commensal microbes induce tissue-resident T cells, but the function of these T cells is not well understood. In this lecture I will present our latest data on the role of commensal Th17 cells in mucosal homeostasis and host physiology. I will explore how commensal Th17 cells in the small intestin...

  • Mercredi 20 Mars 2024 - Séminaire Orateur(s) : Anne Marie Wehenkel

    Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation

    The order Corynebacteriales includes major industrial and pathogenic actinobacteria such as Corynebacterium glutamicum or Mycobacterium tuberculosis. Their elaborate multi-layered cell wall and their polar growth mode impose a stringent coordination between the septal divisome, organized around t...

  • Mercredi 27 Mars 2024 - Séminaire Orateur(s) : David H. Raulet (Molecular and Cell Biology, University of California, Berkeley Esther and Wendy Schekman Chair in Cancer Biology)

    Regulation and immunotherapy responses of NK cells (and T cells) against tumors

    Most immunotherapy efforts aim to mobilize CD8+ T cells against cancer cells. Many tumors lack many neoantigens, and others are selected for partial or complete loss of MHC I, even before immunotherapy intervention.  Checkpoint immunotherapy further exacerbates this problem as it preferentially a...

  • Mercredi 27 Mars 2024 - Séminaire Orateur(s) : Moritz Kreysing

    Biophotonics, Robots, Ghosts

    In this talk, I will discuss two qualitatively new directions in biophotonics: i) FLUCS & interactive microscopy: We have made efforts to understand and control cellular organization through the induction of thermoviscous flows. This includes the non-invasive interference and guidance of PAR p...

  • Jeudi 28 Mars 2024 - Séminaire Orateur(s) : Yonatan STELZER (Weizmann Institute of Science)

    Spatiotemporal models of mammalian development: An epigeneticist’s dream or nightmare?

    My research group aims to address the fundamental challenge of understanding how multicellular organisms achieve variation despite cells having identical genetic information. The development of a single fertilized egg into a complete mammalian embryo is an especially beautiful embodiment of this ...

  • Mercredi 3 Avril 2024 - Séminaire Orateur(s) : Adel Al Jord

    Mechanisms of Organelle Remodeling for Cellular Function

    To function, organisms rely on vital organs which, in turn, rely on specialized cells. At the subcellular scale, cell specialization is notably driven by robust mechanisms of organelle remodeling. Thus, discovering these mechanisms is key for the fundamental understanding of organisms in health a...

  • Jeudi 4 Avril 2024 - Séminaire

    1er séminaire Institut Curie coopération ville-hôpital : Femmes à haut risque de cancer du sein et de l’ovaire

    L'évènement, organisé par Dr Laurence Bozec et Dr Chrystelle Colas, aura lieu le 4 avril 2024 à partir de 16h45, en format présentiel, au sein de l'Institut Curie, site de Saint-Cloud (Salle Bourdin, 35 rue Dailly, 92210).

  • Mercredi 24 Avril 2024 - Séminaire Orateur(s) : Kristina Ganzinger

    High-speed imaging of droplet and vesicle formation during emulsion transfer (cDICE)

    Giant unilamellar vesicles (GUVs) are widely used as in vitro model membranes in biophysics and as cell-sized containers in synthetic biology. Despite their ubiquitous use, there is no one-size-fits-all method for their production. Numerous methods have been developed to meet the demanding requir...

  • Vendredi 26 Avril 2024 - Séminaire Orateur(s) : Julie CARNESECCHI (Institut de Génomique Fonctionnelle de Lyon (IGFL))

    On the multiple roads to cell fate decisions: Integrating transcription factors into RNA-regulatory networks

    While the current view states that Transcription Factors (TFs) act on DNA regulatory elements to deploy precise gene programs, an emerging concept proposes that TFs also bind RNA and regulate splicing to promote molecular and cellular diversity. Yet, how the RNA regulatory functions of TFs contri...

  • Mardi 21 Mai 2024 - Séminaire Orateur(s) : Hironori Funabiki (The Rockefeller University, New York)

    Nucleosomes and DNA methylation – implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancers

    DNA methylation is a broadly observed epigenetic modification. As genomic DNA methylation profiles dynamically change during development and aging, alterations in DNA methylation patterns are linked to diseases such as cancers and immunodeficiency. ICF syndrome is characterized by hypomethylation...

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