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 Monday, 5th, September 2022 - Séminaire Speaker(s) : Joseph Melenhorst (Center for Immunotherapy and ImmunoOncology, Cleveland Clinic, USA) Biological Principles of Chimeric Antigen Receptor-Based T Cell Therapies for Hematological CancersTo be developped soon |
Targeting chromatin regulators in cancerA hallmark of all malignancies is transcriptional dysregulation, which is initiated by recurrent translocations and/or mutations in transcription factors and chromatin regulators. These genetic aberrations manifests as a block in differentiation and an increase in malignant self-renewal. They als... |