Liste des séminaires
How to fit in? Emergence of an apical epithelial cell surface in vivo.Epithelial sheets are crucial components of all metazoan animals, enclosing organs and protecting the animal from its environment. Epithelial homeostasis poses unique challenges, as addition of new cells and loss of old cells must be achieved without disrupting the fluid-tight barrier and apicob... |
Domain 2 Meeting "Nuclear activity and cellular physics at the single cell level"10-10h30: Julien Dumortier (Jean-Léon Maître's team, UMR3215) Title TBD; 10:30-11h: Judith Mine Hattab (Angela Taddei's team, UMR3664) "Gimme a break: Imaging Rad52 dynamics at the single molecule level" 11h-11h30: Michael Schertzer (Arturo Londono's team, UMR3244) Title TBD; 11h30-12h: ... |
Host-parasite coevolutionary arms: Toxoplasma effectors co-opt the host cell (epi)genetic programThe obligate intracellular parasite Toxoplasma gondii strikes a subtle balance with the host immune system that not only prevents host death but also promotes parasite persistence. Although being enclosed within a parasitophorous vacuole (PV), the parasite actively interfaces with host cell signa... |
A Life on HollidayOur genetic material (DNA) is continually subjected to damage, either from endogenous sources such as reactive oxygen species that arise as by-products of oxidative metabolism, from the breakdown of replication forks during cell growth, or by agents in the environment such as ionizing radiation o... |
Hereditary predisposition to childhood brain tumors an underappreciated challenge?It has been well established that pathogenic germline mutations in genes like TP53, PTCH1, SUFU, APC, NF1, SMARCB1, SMARCA4, BRCA2 and the MMR genes are associated with an increased incidence of brain tumors. Most of them are associated with a specific type of brain tumor. It has been estimated t... |
Publishing in Nature GeneticsTiago Faial obtained his Ph.D. from the Stem Cell and Developmental Biology program at the University of Cambridge under the supervision of Jim Smith and Roger Pedersen, where he studied gene regulatory networks and signaling cascades that underpin mesoderm differentiation. For his postdoctoral w... |
Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy EfficiencyOne of the crucial challenges in the clinical management of cancer is resistance to chemotherapeutics. Multidrug resistance (MDR) has been intensively studied, and one of the most prominent mechanisms underlying MDR is overexpression of ATP-binding cassette (ABC) transporters. Despite research ef... |
Chemistry and Cell Biology of Lipid Metabolism - Christoph ThieleThe Thiele group has a long-standing interest in lipids as biomolecules. The biochemistry, cell biology, physiology and immunological aspects of lipids are at the heart of the group's research program. The topics under study include the regulation of lipid anabolism and catabolism at all complexi... |
Marie Sklodowska-Curie Seminar - Christiane Nüsslein-VolhardTitle & abstract to come. |
Domain 2 Seminar - Daniel JaroszTitle & abstract to come. |