Seminars list
 Tuesday, 10th, September 2024 - Séminaire Speaker(s) : Mauro Gaya (Centre d'Immunologie de Marseille Luminy ), Mariolina Salio (Immunocore LTD, Abingdon UK) B cell memory in barrier tissues - " From the bench to the bedside: cancer immunotherapy with soluble T cell receptors"B cell memory in barrier tissues During infection, the immune system unleashes protective responses to fight against the pathogen while also establishes a memory compartment that will provide protection in case of a subsequent pathogen encounters. The B cell memory compartment is composed of t... |
 Tuesday, 10th, September 2024 - Séminaire Speaker(s) : Victor Sourjik Physical limits to bacterial motility and its evolutionary optimizationAlthough all biological systems must obey the laws of physics, specific examples of physical limitations on the performance of biological systems remain sparce. Bacterial motility is among the quantitatively best-understood biological behaviors, and it has long served as a model of how physics ca... |
 Wednesday, 11th, September 2024 - Séminaire Speaker(s) : Yoël Forterre From perception to action without nerves and muscles: lessons from plantsAs sessile organisms, plants face a constantly changing environment with no means of escape. Thus, despite their lack of nerves and muscles, they have evolved unique mechanisms to perceive and respond to external physical signals. In this seminar, I will illustrate this ability through two emblem... |
 Wednesday, 18th, September 2024 - Séminaire Speaker(s) : Pierre Nassoy Engineering, Sorting, Inflating multicellular balloonsOrganoids are lumen-containing multicellular structures that recapitulate key features of the organs. We will first present a microfluidic technology that allows to produce them at high throughput in individual hydrogel capsules. Next, we will show how we can sort cellular aggregates according to... |
New Insights into the Vertebrate Head through Lineage Tracing and Single Cell ApproachesDespite apparent differences between humans and fish, our biological similarities are more profound than commonly recognized. This presentation explores how zebrafish research yields valuable insights into developmental processes, tissue functions, and models for human congenital disorders. Our r... |
 Monday, 23rd, September 2024 - Séminaire Speaker(s) : Thomas Pradeu (CNRS) Why immunologists have no other choice but to do conceptual & theoretical immunologyIn this talk, I argue that immunologists who do not think conceptually and theoretically are very unlikely to make useful contributions to their own field. In a first part, I make three points. First, theories have been crucial in immunology since its inception at the end of the 19th century. Se... |
Use of advanced human lung culture models to study effects of radiotherapyPulmonary radiation toxicity is a main dose-limiting factor of radiotherapy for lung cancer, and manifests primarily as radiation-induced pneumonitis and fibrosis. A variety of mechanisms have been implicated in this toxicity, with a central role of DNA damage following radiation and formation of... |
Morphology meets Genomics Evolution of development in flies , beetles and spidersUnderstanding the evolutionary forces shaping the breathtaking morphological diversity present in nature is one prerequisite to describe and maintain this biodiversity. Linking genetic variation to phenotypic differences is a crucial step towards this goal because information about the appearance... |
RNA-binding proteins in cancer: lessons from CSDE1"RNA-binding proteins (RBPs) modulate all aspects of post-transcriptional gene expression and are increasingly recognized as essential for cancer cell adaptation, reprogramming and stress survival. We aim to identify novel vulnerabilities of metastatic cells that could be harnessed for cancer tre... |
 Wednesday, 2nd, October 2024 - Séminaire Speaker(s) : David Brückner Self-organization and information flow in multicellular systemsA key feature of many developmental systems is their ability to self-organize spatial patterns of functionally distinct cell fates. A spectacular example of this ability are artificial stem cell assemblies, which are paving the way towards a quantifiable self-organization of biological systems. H... |
 Monday, 7th, October 2024 - Séminaire Speaker(s) : Luca Magnani (Institute of Cancer Research) Breast Cancer Dormancy: A Link to the PastLuca Magnani graduated from his bachelor's and master's degree at the University of Bologna. During an exchange visit to Purdue University, he discovered his interest in early embryogenesis. Dr. Magnani's work took him to Michigan State University, where he continued his research on mouse embryog... |
Endocytic control of cell plasticity in cancerOver the past two decades, there has been a significant shift in our understanding of the role of endocytosis and trafficking of signaling receptors. It has evolved from being viewed simply as a signal extinguisher (resulting in long-term attenuation) to being recognized as a sophisticated mechan... |
 Wednesday, 16th, October 2024 - Séminaire Journée cancer du sein et cancers gynécologiquesLe Groupe Sein de l'Institut Curie - Hôpital à Saint-Cloud a, comme chaque année, le plaisir de vous inviter à sa demi-journée conscrée aux cancers de la femme, dans le but de présenter et de discuter ensemble les aspects pratiques de la prise en charge et l'évolution des connaissances dans ce do... |
Protein structure and membrane dynamics in the endolysosomal system. |
Crystal ribcage: a platform for probing real-time lung function at cellular resolution in health and diseaseUnderstanding the dynamic pathogenesis and treatment response in pulmonary diseases requires probing the lung at cellular resolution in real-time. Despite recent progress in intravital imaging, optical imaging of the lung during active respiration and circulation has remained challenging. Here, I... |
Immune-brain communication at the choroid plexusIt is now accepted that blood-derived immune cells and microbial products shape brain development, function, aging, and disease, yet the presence of such factors in the brain territory is limited. So how can they exert their powerful effect on the nervous system from afar? The choroid plexus (... |
 Wednesday, 12th, March 2025 - Séminaire Speaker(s) : Thorsten Hugel Compartment-specific protein dynamics and signalling in living cells revealed by smFRETProteins in cells are not homogeneously distributed, but often localized to specific compartments, which may or may not be enclosed by membranes. Here I will first discuss the dynamic formation of membraneless compartments in the non-equilibrium environment of living cells and how this formati... |