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  • Tuesday, 28th, May 2019 - Séminaire Speaker(s) : Stephen KOWALCZYKOWSKI (University of California, Department of Microbiology and Molecular Genetics, Department of Molecular and Cellular Biology, Davis, USA, Chaires Blaise Pascal, Région Ile de France)

    Molecular Mechanism of Chromosome Maintenance by Homologous Recombination: Seeing and Understanding BRCA2 and RAD51 Functions

    Molecular Mechanism of Chromosome Maintenance by Homologous Recombination: Seeing and Understanding BRCA2 and RAD51 Functions

  • Wednesday, 29th, May 2019 - Séminaire Speaker(s) : Francesca Bartolini (Columbia University, New York, USA)

    Microtubule Regulating Pathways in Synaptic Injury and Bortezomib-Induced Axonal Degeneration

    Emerging studies from several groups have indicated that dynamic microtubules, in addition to modified microtubules, play key roles in neuronal function. In addition, synaptic biphasic fluctuations of microtubule instability/stability and tubulin post-translational modifications (PTMs) have recen...

  • Friday, 7th, June 2019 - Séminaire Speaker(s) : Kumar Somyajit (Jiri Lukas laboratory Novo Nordisk Foundation Center for Protein Research University of Copenhagen Denmark)

    The dynamic coupling between metabolic signaling and genome surveillance mechanisms

    Faithful and complete duplication of genome relies on the precise regulation of DNA replication and protection of newly synthesized DNA. Globally, DNA replication is determined by the frequency of replication initiation and the speed of individual forks. While the series of events required for in...

  • Wednesday, 19th, June 2019 - Séminaire Speaker(s) : Colin Logie (Radboud Institute for Molecular Life Sciences)

    Epigenetic programming of macrophage differentiation and glucocorticoid responses

    The molecular basis of cellular memory is a current knowledge frontier. In the immune system, cellular memory likely extends beyond cell fate determination mechanisms since immunity can tailor its responses to a potentially hostile environment that is a priori variable if not unpredictable. One p...

  • Thursday, 20th, June 2019 - Séminaire Speaker(s) : Trey IDEKER (UC San Diego School of Medicine)

    Decoding tumor genomes through the hierarchical pathway architecture of the cancer cell

    Although cancer is governed by complex molecular systems, the composition and modular organization of these systems remains poorly understood. I will describe efforts by the Cancer Cell Map Initiative (CCMI) to generate large protein interaction maps of tumor cells, which we are integrating with ...

  • Thursday, 20th, June 2019 - Séminaire Speaker(s) : Julie Gavard (UMR_S 1232 Centre de Recherche en Cancérologie et Immunologie Nantes-Angers)

    Paracrine Communication between Stem-like Cells and Endothelial Cells in Glioblastoma

    Glioblastoma (GBM) are the most common and aggressive primary brain tumors and among the most lethal forms of adult cancer. Current therapeutic approaches consist of maximal surgical resection followed by chemo- and radiotherapy. However, this regimen is largely ineffective and GBM almost invaria...

  • Friday, 21st, June 2019 - Séminaire

    Démocratie sanitaire en recherche - journée SIRICs et Cancéropôle francilien

    Le Cancéropôle Île-de-France et les 4 SIRICs franciliens CARPEM, Curie, CURAMUS et SOCRATE s'associent pour organiser le 21 juin 2019 une journée sur le sujet de la démocratie sanitaire en recherche dans le domaine du cancer à l'amphithéâtre Constant Burg. Le concept de démocratie sanitaire en...

  • From Wednesday, 5th, June 2019 To Friday, 5th, July 2019 - Séminaire Speaker(s) : Ilya Levental (McGovern Medical School, University of Texas Health Science Center at Houston, USA)

    The structure and function of the mammalian plasma membrane

    The plasma membrane is the interface between a cell and its environment, and is therefore responsible for a myriad of parallel processing tasks that must be tightly regulated to avoid aberrant signaling. To achieve this functional complexity, mammalian cells produce hundreds of lipid species that...

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