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  • Mercredi 28 Juin 2017 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Cécile Fradin (Université McMaster d’Hamilton, Canada)

    How many Bcl-2 family proteins does it take to form a pore in a lipid membrane?

               Proteins from the Bcl-2 family preside over what is essentially the “point-of-no-return” in apoptosis. Pro-apoptotic members of the family promote outer mitochondrial membrane permeabilization and cell death, while anti-apoptotic members promote cell survival by blocking th...

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