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  • Mardi 13 Novembre 2018 - Séminaire Cell Biology Series Orateur(s) : Lukas HUBER, PhD

    LAMTOR and BORC regulate the position and size of late endosomes/lysosomes

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  • Mardi 20 Novembre 2018 - Séminaire Cell Biology Series Orateur(s) : Ruth KROSCHEWSKI (ETH Zurich - Institute of Biochemistry, Zurich)

    Plasmid DNA transfection, revealing tolerant yet separatist mammalian cells

    The genome of mammalian cells is challenged by extra-chromosomal DNA introduced by viruses, bacteria, or transfection of plasmid DNA. However, how cells handle these DNA molecules is largely unknown. We analyzed predominantly Hela cells stably expressing fluorescently tagged LacI protein and t...

  • Mardi 27 Novembre 2018 - Séminaire Cell Biology Series Orateur(s) : Winnok H. DE VOS, PhD

    NUC-I-LEAKS. EXPOSING THE MECHANISMS THAT COMPROMISE NUCLEAR ENVELOPE INTEGRITY IN HUMAN CANCER CELLS

    The nuclear envelope (NE) has long been considered to dismantle only during mitosis. However, recent observations in cancer cells and laminopathy patient cells have revealed that the NE can also transiently rupture during interphase, thereby perturbing cellular homeostasis and genome stability (1...

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