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  • Mercredi 13 Mars 2019 - Séminaire institutionnel "Marie Curie Seminar" Orateur(s) : John Marko (Department of Molecular Biosciences, Northwestern University, Evanston, USA)

    Mechanics, topology and geometry of mammalian chromosomes and nuclei and their modulation by histone epigenetic marks

    Our lab uses biophysical methods, with particular emphasis on micromanipulation of single DNA molecules and single chromosomes, to study the internal structure of chromosomes in vivo, and to study chromosome-organizing proteins and DNA topoisomerases in vitro. We also develop mathematical models ...

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