High parameter single-cell proteins and RNAs analysis: from new technologies to cancer immunology
The goal of this seminar is to give an overview on my past work, as well as to introduce the questions that my group will aim at addressing.
I will showcase few single-cell technologies that my colleagues and I have developed at Stanford University, which apply to multiplexed imaging, mass cytometry and sequencing.
I will then briefly touch upon two biological questions that I have being trying to address. One of these two will also be the main focus of our laboratory: why is the immune system not capable of eradicating cancer cells? Our angle on such popular question (these days) focuses onto the gene regulatory mechanisms underlying T-lymphocytes exhaustion.
This seminar is intended to serve as primer for discussion later-on the same day, with anyone interested in meeting with us.
Junior Principal Investigator