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Seminar

Thursday, July 6th, 2023
10h
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)

Cellular and environmental mechanisms regulating protein absorption in the vertebrate gut

Intestinal epithelial cells (IECs) are highly polarized and can perform vectorial transport of nutrients using asymmetrically localized membrane proteins and via polarized endocytic and trafficking processes. Using cell biological, forward and reverse genetics, and physiology approaches, we have been investigating mechanisms regulating cell polarization and protein absorption in zebrafish and mice. I will share recent results revealing posttranscriptional mechanisms regulating apical polarization and ongoing studies on how the interaction between diet, microbes, and lysosome rich enterocytes regulates protein absorption.

Speaker(s)

Michel BAGNAT
PhD

Professor of Cell Biology, Duke University Medical Center

Invited by

Pedro HERNANDEZ
Génétique et biologie du développement (UMR3215 / U934)

Institut Curie

Contact

Pedro HERNANDEZ

Institut Curie

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