Transposable Elements as Catalysts of Regulatory Evolution
Eukaryotic genomes are replete with sequences derived from selfish genetic elements, such as transposable elements and endogenous viruses. In this talk, I will present a snapshot of the myriad ways these elements have influenced the biology of their hosts. I will summarize a body of evidence illustrating how both coding and non-coding sequences prefabricated and dispersed by mobile elements have been repurposed repeatedly during vertebrate evolution to foster biological novelties –-and particularly in transcriptional regulation.
Professor, Department of Molecular Biology and Genetics
Cornell University, Ithaca, NY, US
Génétique et biologie du développement (UMR3215 / U934)