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Seminar

Thursday, October 18th, 2018
14h30
Centre de Recherche - Paris - Amphith√©√Ętre Marie Curie

Molecular Architecture and Physiological Function of Caveolae

Caveolae are an abundant feature of the plasma membrane of many mammalian cells, but the cell biology of these structures remains incompletely understood. My seminar will present recent data on the protein complexes that generate caveolae, including a large complex to determine the size and membrane shape of caveolae and a smaller complex that plays a role in the higher-order assembly of clusters of caveolae. I will also present a polemical view of the function of caveolae, arguing that much of the published experimental data can be explained by a simple model in which caveolae act as buffers for mechanical tension within the membrane.

Speaker(s)

Dr. Ben Nichols

MRC Laboratory of Molecular Biology Francis Crick Avenue Cambridge CB2 0QH

Hosted by

Dr. Christophe Lamaze

Invited by

Dr. Christophe Lamaze
Domain 4 - UMR 3666 / U1143 - Chemical Biology of Membranes and Therapeutic Delivery

Institut Curie

Contact

M. Yannick Bono

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