Tissue dynamics in development and repair
Actomyosin contractility is a key regulator of tissue dynamics. During development, tissue dynamics, such as cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how tissues respond to mechanical perturbations, such as stretching or wounding, by altering their actomyosin contractile structures, to change tissue dynamics, and thus preserve tissue shape and patterning.
MRC - Laboratory for Molecular Cell Biology, University College London
Domain 2 - UMR 3215 / U934 - Genetics and Developmental Biology