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Vendredi 16 Février 2018
De 14h à 15h30
Centre de Recherche - Paris - Amphithéâtre Constant-Burg (12 rue Lhomond, Paris 5e) en visio-conférence avec l'amphithéâtre du bâtiment 111 (Orsay) et salle Clavel (Saint-Cloud)

The cancer epigenome: Concepts, challenges, and therapeutic opportunities

Cancer biology is profoundly influenced by changes in the epigenome. Because the dynamic plasticity of the epigenome lends itself well to therapeutic manipulation, the past few years have witnessed an unprecedented investment in the development,characterization, and translation of targeted epigenetic therapies. In this seminar, I will provide a broad context for recent developments that offer a greater understanding of how epigenetic regulators facilitate the initiation, maintenance, and evolution of cancer. I will discuss newly developed epigenetic therapies and the cellular and molecular mechanisms that may govern sensitivity and resistance to these agents. I will also review the rationale for future combination therapies involving existing and emerging epigenetic drugs.


Mark Dawson

Peter MacCallum Cancer Centre Victorian Comprehensive Cancer Centre building


Raphael Rodriguez

Invité(e)(s) par

Raphaël Rodriguez


Yannick Bono

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