Seminars list
![]() Intrinsic disorder at membrane contact site facilitates protein diffusion___ |
![]() GRASP65 and 55 and unconventional secretion in the gut___ |
![]() Novel roles of the centrosome protein ninein in mouse developmentWe have generated mice in which the gene of the microtubule-organizing protein ninein was knocked out constitutively, and specifically in the epidermis. Both types of mice showed epidermal defects during embryonic development, leading to a compromised skin barrier. At the cellular level, keratino... |
![]() Chemotaxis in pancreatic ductal adenocarcinoma metastasis: An unexpected role of N-WASP in receptor trafficking: Pancreatic ductal adenocarcinoma is one of the most invasive and metastatic cancers and has a dismal 5-year survival rate. We find that N-WASP is required for the metastatic process, with roles in chemotaxis, steering cells out of primary tumours, and matrix remodelling. Lysophosphatidic acid... |
![]() Reorganization of membrane traffic during fungal morphogenesis___ |
![]() Mapping molecular assemblies with super resolution using ICY SODA colocalization analysis & new membrane probes (the MemBright family)Elucidating molecular organization and protein functions requires localizing precisely single or aggregated molecules and analyzing their spatial distributions. We develop a statistical method SODA (Statistical Object Distance Analysis) that uses either micro- or nanoscopy to significantly improv... |
![]() In vitro reconstitution of cell tissue morphogenesis___ |
![]() Innate immune responses to chromosomal instability: APOBEC base editing and cGAS activation___ |
![]() Molecular insights into cholesterol recognition by a signaling transmembrane receptor___ |
![]() Commitment to mitosis: No need to run, must leave on time___ |