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  • Jeudi 24 Janvier 2019 - Séminaire institutionnel "Marie Curie Seminar" Orateur(s) : Richard D Cummings,

    Integration of Glycomics, Development, and Immunology

    Ludger Johannes has invited  Pr Richard D. Cummings from Beth Israel Deaconess Medical Center Harvard Medical School to come and give a talk on "Integration of Glycomics, Development, and Immunology". He will also participate in the Pastor's course

  • Mardi 29 Janvier 2019 - Séminaire Cell Biology Series Orateur(s) : Julien DUMONT (Institut Jacques Monod - Cell Division and Reproduction )

    Probing the Mechanisms of Chromosome Segregation with C. elegans

    During cell division, accurate chromosome segregation ensures the genetic integrity of cells and organisms, and shields them against aneuploidy, a hallmark of many cancers. By using the nematode Caenorhabditis elegans, we have gained important insights into the machinery and mechanisms that contr...

  • Mercredi 30 Janvier 2019 - Séminaire Orateur(s) : Doron Grossman (The Hebrew University of Jerusalem)

    From Molecules to Helical Ribbons - Shape and Shape Fluctuations

    Self assembly of molecules into supramolecular structures is an important process through which non trivial structures are formed in nano-metric scale. The resulting structure depends on chemical and physical principles that govern the process, and may be sensitive to the exact conditions in whic...

  • Mercredi 30 Janvier 2019 - Séminaire Orateur(s) : Amandine Pluchet (Responsable des services à la recherche de l’Université Paris-Saclay)

    Enhancing the visibility and accessibility of research : Open Access and bibliometrics

    Amandine Pluchet abordera entre autres : comment déposer une publication dans un archive ouverte (HAL, ArXiv….), publier dans une revue Open Access,  l'utilisation des licences Créatives Communs pour diffuser sa production scientifique, les aspects de bibliométrie (usages, critères, indica...

  • Mercredi 30 Janvier 2019 - Séminaire Orateur(s) : Yuyu SONG (Havard University Medical School, Boston, USA)

    Motor neuron disease and microtubule cytoskeleton: highways and scaffolds for signaling

    Microtubules (MTs) are structural components vital for important neuronal functions including neurite outgrowth and maintenance, as well as axonal trafficking and synaptic remodeling. Heterozygous missense mutations in specific tubulin genes, such as TUBA1, TUBB2B, and TUBB3 have been associated ...

  • Mardi 5 Février 2019 - Séminaire Nuclear dynamic series Orateur(s) : Sandra Duharcourt (Institut Jacques Monod)

    Lessons from Paramecium genome gymnastics : A dual histone H3 K9/K27 Polycomb protein ensures transposable element repression

    In animals and plants, the H3K9me3 and H3K27me3 chromatin silencing marks are deposited by different protein machineries and play distinct cellular roles. We show that the Enhancer-of-zeste-like protein Ezl1 from the unicellular eukaryote Paramecium tetraurelia, which exhibits significant sequenc...

  • Mardi 5 Février 2019 - Séminaire Orateur(s) : Cindy Neuzillet (Institut Curie)

    Inter- and intra-tumoral heterogeneity and dynamics of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma and implications for immune therapy

    Cancer-associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential pathophysiological roles of the stroma (pro- vs. anti-tumoral) in PDAC. We hypothesised that multiple CAF subtypes exist in PDAC th...

  • Vendredi 8 Février 2019 - Séminaire Orateur(s) : Bradley R. Cairns (Huntsman Cancer Institute, Salt Lake City)

    Bradley R. Cairns: Chromatin and Transcription Dynamics in the Germline and Early Embryos

    If you would like to meet the speaker, please contact Deborah.Bourchis@curie.fr

  • Vendredi 8 Février 2019 - Séminaire Orateur(s) : Dmitry Bulavin (Institute for Research on Cancer and Aging, IRCAN Nice)

    Senescence as a conundrum of life and death

    Aging is the major risk factor for many chronic diseases accounting for the bulk of morbidity, mortality, and health costs in the world. There is significant evidence that the accumulation of senescent cells can drive many phenotypes and pathologies associated with aging. How senescence mechanist...

  • Lundi 11 Février 2019 - Séminaire Immunology series Orateur(s) : Gunnar Schotta (Biomedical Center, LMU Munich, Munich, Germany)

    Silencing Mechanisms of endogenous retroviruses

    Epigenetic mechanisms regulate multiple aspects of normal development (stem cell maintenance, differentiation). Misregulation of epigenetic programs can result in aberrant development (cancer, aging). In this context we study the mechanisms of epigenetic gene regulation using a combination of mou...

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