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  • Mercredi 17 Avril 2024 - Séminaire Orateur(s) : Sophie Marbach

    The Countoscope: Measuring Dynamics by Counting Particles in Boxes

    Any imaging technique is limited by lts field of view. As objects or particles move in and out of the observation field, tracking their motion, especially over long periods, beoomes challenging. ln addition, available analysis techniques face challenges reconstructing trajectories in dense and he...

  • Lundi 22 Avril 2024 - Séminaire Immunology series Orateur(s) : Mikael Pittet (Faculty of Medicine, University of Geneva, Full Member, Ludwig Institute for Cancer Research, Geneva University Hospitals (HUG) & Swiss Cancer Center Leman (SCCL))

    Microenvironmental coordination in the control of human cancers

    My lab is dedicated to discovering how the immune system controls cancer and how it can be harnessed for therapeutic purposes. Our work has helped identify how certain cancers are regulated by various immune cells, including cytotoxic T-cells, regulatory T-cells, macrophages, monocytes, neutrophi...

  • Mardi 23 Avril 2024 - Séminaire Nuclear dynamic series Orateur(s) : Benjamin Loppin (Laboratoire de Biologie et Modélisation de la Cellule - ENS Lyon)

    Establishing a paternal chromosome identity in the Drosophila male germline

    In many animals, mature sperm chromatin is organized with sperm-specific chromosomal proteins known as protamines. Complete or partial elimination of nucleosomes occur during the histone-to-protamine transition, a complex chromatin reorganization process that takes place during spermiogenesis, th...

  • Mercredi 24 Avril 2024 - Séminaire Orateur(s) : Kristina Ganzinger

    High-speed imaging of droplet and vesicle formation during emulsion transfer (cDICE)

    Giant unilamellar vesicles (GUVs) are widely used as in vitro model membranes in biophysics and as cell-sized containers in synthetic biology. Despite their ubiquitous use, there is no one-size-fits-all method for their production. Numerous methods have been developed to meet the demanding requir...

  • Jeudi 25 Avril 2024 - Séminaire Orateur(s) : Roberto MAYOR (University College London, UK)

    Mechanics of Neural Crest Development: From Induction to Migration and Differentiation

    The neural crest is an embryonic cell population whose migratory behavior has been likened to cancer invasion during metastasis. Neural crests differentiate into a wide array of cell types, including muscle, cartilage, bones, melanocytes, neurons, and glia. Although the role of mechanical cues ha...

  • Vendredi 26 Avril 2024 - Séminaire Orateur(s) : Julie CARNESECCHI (Institut de Génomique Fonctionnelle de Lyon (IGFL))

    On the multiple roads to cell fate decisions: Integrating transcription factors into RNA-regulatory networks

    While the current view states that Transcription Factors (TFs) act on DNA regulatory elements to deploy precise gene programs, an emerging concept proposes that TFs also bind RNA and regulate splicing to promote molecular and cellular diversity. Yet, how the RNA regulatory functions of TFs contri...

  • Du Lundi 22 Avril 2024 Au Vendredi 26 Avril 2024 - Cours international - séminaire

    Mécanique des tissus, mémoire et métabolisme - 6e édition Biologie Cellulaire et Cancer

    L'objectif général du 6ème cours de biologie cellulaire et de cancérologie est de couvrir différents sujets de biologie cellulaire et de physique, en se concentrant sur la mécanique des tissus, l'effet de mémoire et le métabolisme cellulaire. Le cours couvrira des sujets tels que la polarité cell...

  • Jeudi 2 Mai 2024 - Séminaire institutionnel "Mayent - Rothschild" Orateur(s) : Claude DESPLAN (NYU Department of Biology)

    THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTION

    Claude Desplan1,2, Nikos Konstantinides1, Felix Simon1, Neset Ozel1, Isabel Holguera1, Jennifer Malin1, Yen Chen1, and Bogdan Sieriebriennikov1   1 Center for Developmental Genetics, Department of Biology, New York University, New York, USA; 2 Center for Genomics and System Biology, NYU Abu...

  • Vendredi 3 Mai 2024 - Séminaire Orateur(s) : Anne Brunet (Stanford University School of Medicine)

    Understanding and modeling aging

    Aging is associated with a decline in tissue function and the onset of a constellation of diseases. We are interested in understanding aging, with a particular focus on brain aging. Because aging is complex, we use organisms with diverse lifespans – the worm C. elegans, the African killifis...

  • Lundi 13 Mai 2024 - Séminaire Orateur(s) : Jeroen Roose (University of California, San Francisco)

    “Deconstruct-Reconstruct” – Decode cancer-immune crosstalk & probe with organoids.

    The Roose team at UCSF studies mechanisms of cell-cell interactions in immunology and cancer1-7, with emphasis on personalized medicine4,8 and single cell approaches9-11. Over the past 7 years, we shifted a large portion of our research efforts to understanding human biology and disease. We are d...

  • Mardi 21 Mai 2024 - Séminaire Orateur(s) : Hironori Funabiki (The Rockefeller University, New York)

    Nucleosomes and DNA methylation – implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancers

    DNA methylation is a broadly observed epigenetic modification. As genomic DNA methylation profiles dynamically change during development and aging, alterations in DNA methylation patterns are linked to diseases such as cancers and immunodeficiency. ICF syndrome is characterized by hypomethylation...

  • Du Mercredi 22 Mai 2024 Au Mercredi 29 Mai 2024 - Cours international - séminaire

    Génome non-codant

    Le cours « NON-CODING GENOME » explorera la diversité des éléments d'ADN non géniques et des ARN non codants dans un large spectre de processus cellulaires, chez l'homme et les organismes modèles, ainsi que leur implication dans la physiologie et la pathologie. Des experts de renommée internation...

  • Vendredi 31 Mai 2024 - Séminaire Orateur(s) : Wei Yang (National Institute of Health - NIH)

    Cutting and Pasting DNA to Create our Adaptive Immune System

    V(D)J recombination is essential for generating the adaptive immune response and unlimited number of different antibodies and antigen receptors. Encoded by multiple V, D and J gene segments, antigen receptors are assembled by programmed double-stranded DNA cleavage and imprecise re-joining. RAG1/...

  • Mardi 15 Octobre 2024 - Séminaire Orateur(s) : Sara Lucia Giustina Sigismund

    Endocytic control of cell plasticity in cancer

    Over the past two decades, there has been a significant shift in our understanding of the role of endocytosis and trafficking of signaling receptors. It has evolved from being viewed simply as a signal extinguisher (resulting in long-term attenuation) to being recognized as a sophisticated mechan...

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