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  • Lundi 10 Mai 2021 - Séminaire Immunology series Orateur(s) : Marc Bajénoff (CIML, Marseille, France)

    Stroma-Macrophage Two Cell Circuits

    Macrophages sustain tissue homeostasis within the body through trophic, regulatory and repair functions. Macrophage homeostasis is locally regulated by “niches." Although this concept has recently found great appreciation in the field, the very nature of these niches and the molecular dialo...

  • Mercredi 12 Mai 2021 - Séminaire Physico-Chimie Orateur(s) : Anton Goloborodko (IMBA Vienna, Austria)

    Unraveling the structure of paired homologs and sister chromatids with Hi-C and polymer modeling

    The genomes of living organisms are stored on DNA molecules, called chromosomes, which are typically present in multiple copies. For example, diploid organisms have two slightly different copies of each chromosome, called homologs. Moreover, in preparation for division, cells duplicate their chro...

  • Mercredi 19 Mai 2021 - Séminaire Physico-Chimie Orateur(s) : Sophie Brasselet (Institut Fresnel, Marseille)

    Super resolution imaging of proteins’ organization in 3D using polarized single molecule localization

    Imaging molecular orientation at the nanoscale in live cells and tissues is fundamental in the understanding of proteins' organization, which is driven by their structural and conformational properties. Measuring fluorescent molecules' orientation is an interesting way to approach this problem, p...

  • Mercredi 19 Mai 2021 - Séminaire Orateur(s) : Elana J. FERTIG (Johns Hopkins University)

    Enter the matrix: modeling tumor cell and immune cell interactions at the single cell resolution

    Tumors employ complex, multi-scale cellular and molecular interactions that evolve over the course of therapeutic response. The changes in these pathways enables tumors to overcome therapeutic regimens, and ultimately acquire resistance. New molecular profiling technologies, including notably sin...

  • Vendredi 21 Mai 2021 - Webinaire Orateur(s) : Olivier Delattre (Institut Curie)

    STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

    STAG2, a cohesin family gene, is among the most recurrently mutated genes in cancer. STAG2 loss-of-function (LOF) is associated with aggressive behavior in Ewing sarcoma, a childhood cancer driven by aberrant transcription induced by the EWSR1-FLI1 fusion oncogene. Here, using isogenic Ewing cell...

  • Mardi 25 Mai 2021 - Webinaire

    Inscrivez-vous à l'événement virtuel "ADAPT to Thrive" sur l'échec et la résilience!

    University College London, UMC Utrecht et l'Institut Curie s'associent pour organiser un événement virtuel le 25 mai dans le cadre de la série d'événements ADAPT to Thrive sur l'échec et la résilience. Vous voulez savoir comment des universitaires et des chercheurs accomplis ont échoué et ont ...

  • Du Lundi 13 Décembre 2021 Au Mardi 14 Décembre 2021 - Congrès Orateur(s) : Suzana Hadjur (UCL), Timothee Lionnet (NYU), Karen Miga (UCSC), Didier Trono (EPFL)

    Epigene2sys online meeting 2021

    Epigene2Sys is a CNRS GDRi, coordinated by G. Almouzni (CNRS, Paris) and M-E Torres Padilla (HGMU, Munich), was launched in 2018 in continuation to the EpiGeneSys Network of Excellence,  with the aim to stimulate discoveries and discussions in epigenetics research and to encourage equal opportuni...

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