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  • Mardi 3 Novembre 2020 - Séminaire Cell Biology Series Orateur(s) : Alexis GAUTREAU

    Assembly of an Actin Polymerizing Machine: The WASH – Dynactin – Arp2/3 Supercomplex

    I will discuss recent results dealing with the assembly of the WASH complex in centrosomes and how WASH primes the formation of branched actin networks at the surface of endosomes through the uncapping of Dynactin.

  • Mardi 24 Novembre 2020 - Séminaire Nuclear dynamic series Orateur(s) : Christian Lesterlin (Institut de Biologie et Chimie des Protéines)

    Real-time visualization of drug resistance acquisition by horizontal gene transfer reveals a new role for AcrAB-TolC multidrug efflux pump

    Drug resistance dissemination by horizontal gene transfer remains poorly understood at the cellular scale. Using live-cell microscopy, we reveal the dynamics of resistance acquisition by transfer of the F conjugative plasmid encoding the tetracycline-efflux pump TetA. We show that the entry of th...

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