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  • Mardi 18 Janvier 2022 - Séminaire Nuclear dynamic series Orateur(s) : Jakub Wiktor ( Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden)

    The reduced-dimensionality mechanism of homology search by RecA filament during double stranded break repair

    Homologous recombination is essential for the accurate repair of double-stranded DNA breaks (DSBs). Initially, the RecBCD complex resects the ends of the DSB into 3′ single-stranded DNA on which a RecA filament assembles. Next, the filament locates the homologous repair template on the sist...

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